VTG2 vitellogenin 2 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: VTG2provided by CGNC
Official Full Name: vitellogenin 2provided by CGNC
Primary source: CGNC:52212
See related: Ensembl:ENSGALG00010020856
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: vit; VIT2; vitellogenin-2
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Genomic context

Location:: chromosome: 8

Exon count:: 35

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	8	NC_052539.1 (16204330..16225309)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	8	NC_052580.1 (16213493..16234477)

Chromosome 8 - NC_052539.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

C-Terminal Fragment of Vitellogenin II, a Potential Yolkin Polypeptide Complex Precursor Protein-Heterologous Expression, Purification, and Immunoregulatory Activity.
Title: C-Terminal Fragment of Vitellogenin II, a Potential Yolkin Polypeptide Complex Precursor Protein-Heterologous Expression, Purification, and Immunoregulatory Activity.
for the first time generated a large number of phosphopeptides (~100) and identified 151 phosphorylation sites of phosvitin 1 and phosvitin 2, respectively. Importantly, this study also led to the discovery of a novel phosvitin 1
Title: Topographical distribution of phosphorylation sites of phosvitins by mass spectrometry.
Data show that hepatocellular carcinoma LMH cells transfected with a reporter construct bearing the vitellogenin promoter is a useful model for the study of hydrocarbon receptor (AHR)-estrogen receptor (ER) interaction in liver-derived cells.
Title: Aryl hydrocarbon receptor activation leads to impairment of estrogen-driven chicken vitellogenin promoter activity in LMH cells.
Results describe the efects of daidzein, alone or in combination with estrogen, on estrogen receptor alpha and/or beta-mediated transactivation and on chicken hepatic vitellogenin II expression.
Title: Dual effects of daidzein on chicken hepatic vitellogenin II expression and estrogen receptor-mediated transactivation in vitro.

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General gene information

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Markers

VTG2sts1 (e-PCR), detects polymorphism
- UniSTS:280371

VTG2sts2 (e-PCR), detects polymorphism
- UniSTS:280372

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables lipid transporter activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lipid transport	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: vitellogenin-2

Names: major vitellogenin; vitellogenin II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031276.2 → NP_001026447.2 vitellogenin-2 precursor

Status: VALIDATED

Source sequence(s)

JAENSK010000239

UniProtKB/Swiss-Prot

P02845, Q6LBT2, Q91026, Q91027

UniProtKB/TrEMBL

A0A8V0Z932

Related

ENSGALP00010029785.1, ENSGALT00010050464.1

Conserved Domains (2) summary

smart00216
Location:1584 → 1749

VWD; von Willebrand factor (vWF) type D domain

smart00638
Location:34 → 602

LPD_N; Lipoprotein N-terminal Domain