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MYSM1 Myb like, SWIRM and MPN domains 1 [ Gallus gallus (chicken) ]

Gene ID: 424671, updated on 3-Dec-2024

Summary

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Symbol
MYSM1provided by CGNC
Full Name
Myb like, SWIRM and MPN domains 1provided by CGNC
Primary source
CGNC:8259
See related
Ensembl:ENSGALG00010026780
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MYSM1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (26011417..26026349, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (26024611..26039550, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene OMA1 zinc metallopeptidase Neighboring gene ankyrin-3-like Neighboring gene tumor associated calcium signal transducer 2 Neighboring gene FGGY carbohydrate kinase domain containing Neighboring gene Jun proto-oncogene, AP-1 transcription factor subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BRCA1-A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of BRISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone H2A deubiquitinase MYSM1
Names
2A-DUB
myb-like, SWIRM and MPN domain-containing protein 1
NP_001012945.2
XP_015146508.2
XP_015146509.2
XP_040560616.1
XP_040560617.1
XP_046778804.1
XP_046778805.1
XP_046778806.1
XP_046778807.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012927.2 → NP_001012945.2  histone H2A deubiquitinase MYSM1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000239
    UniProtKB/Swiss-Prot
    Q5F3F2
    Related
    ENSGALP00010039677.1, ENSGALT00010064975.1
    Conserved Domains (3) summary
    cd08067
    Location:573 → 755
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
    COG5259
    Location:382 → 466
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:121 → 164
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    26011417..26026349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291023.4 → XP_015146509.2  histone H2A deubiquitinase MYSM1 isoform X2

    UniProtKB/Swiss-Prot
    Q5F3F2
    Conserved Domains (3) summary
    cd08067
    Location:573 → 742
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
    COG5259
    Location:382 → 466
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:121 → 164
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

  2. XM_040704682.2 → XP_040560616.1  histone H2A deubiquitinase MYSM1 isoform X3

    UniProtKB/Swiss-Prot
    Q5F3F2
    UniProtKB/TrEMBL
    A0A8V1A6G0
    Related
    ENSGALP00010039676.1, ENSGALT00010064972.1
    Conserved Domains (3) summary
    cd08067
    Location:573 → 730
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
    COG5259
    Location:382 → 466
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:121 → 164
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

  3. XM_015291022.4 → XP_015146508.2  histone H2A deubiquitinase MYSM1 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3F2
    Conserved Domains (3) summary
    cd08067
    Location:573 → 755
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
    COG5259
    Location:382 → 466
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:121 → 164
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

  4. XM_040704683.2 → XP_040560617.1  histone H2A deubiquitinase MYSM1 isoform X4

    UniProtKB/Swiss-Prot
    Q5F3F2
    Conserved Domains (3) summary
    cd08067
    Location:573 → 755
    MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
    COG5259
    Location:382 → 466
    RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
    cd00167
    Location:121 → 164
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    26024611..26039550 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922849.1 → XP_046778805.1  histone H2A deubiquitinase MYSM1 isoform X2

    UniProtKB/Swiss-Prot
    Q5F3F2

  2. XM_046922850.1 → XP_046778806.1  histone H2A deubiquitinase MYSM1 isoform X3

    UniProtKB/Swiss-Prot
    Q5F3F2

  3. XM_046922848.1 → XP_046778804.1  histone H2A deubiquitinase MYSM1 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3F2

  4. XM_046922851.1 → XP_046778807.1  histone H2A deubiquitinase MYSM1 isoform X4

    UniProtKB/Swiss-Prot
    Q5F3F2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5F3F2.1 GenPept UniProtKB/Swiss-Prot:Q5F3F2

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