Mvl - Malvolio
Enables symporter activity and transition metal ion transmembrane transporter activity. Involved in several processes, including positive regulation of iron ion transmembrane transport; sensory perception of sweet taste; and transition metal ion transport. Located in endosome and plasma membrane. Is expressed in several structures, including Malpighian tubule; embryonic/larval hemocyte; gland; gut section; and organism subdivision. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease (multiple); inflammatory bowel disease (multiple); leishmaniasis (multiple); and tuberculosis (multiple). Orthologous to several human genes including SLC11A2 (solute carrier family 11 member 2). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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