POLR2H RNA polymerase II subunit H [Gallus gallus (chicken)] - Gene

Summary

Symbol: POLR2Hprovided by CGNC
Full Name: RNA polymerase II subunit Hprovided by CGNC
Primary source: CGNC:6474
See related: Ensembl:ENSGALG00010015987
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 9

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (15646550..15648498, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (15440283..15442231, complement)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RNA sequencing results revealed that the chicken POLR2H was differently expressed between the intestinal mucosal layer of Necrotic enteritis induced chicken lines that are resistant and sensitive to avian leukosis and Marek's disease.
Title: Expression analysis of cytosolic DNA-sensing pathway genes in the intestinal mucosal layer of necrotic enteritis-induced chicken.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of RNA polymerase I complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of RNA polymerase II, core complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of RNA polymerase III complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: DNA-directed RNA polymerases I, II, and III subunit RPABC3

Names: polymerase (RNA) II (DNA directed) polypeptide H; polymerase (RNA) II subunit H

NP_001264394.1

EC 2.7.7.6

NP_001264396.1

EC 2.7.7.6

NP_001264397.1

EC 2.7.7.6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277465.1 → NP_001264394.1 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1

See identical proteins and their annotated locations for NP_001264394.1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

Source sequence(s)

BU228669, BX931358, CF256811, CR353858

UniProtKB/TrEMBL

E1BSD8

Related

ENSGALP00010022294.1, ENSGALT00010038528.1

Conserved Domains (1) summary

smart00658
Location:2 → 147

RPOL8c; RNA polymerase subunit 8
NM_001277467.1 → NP_001264396.1 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 2

See identical proteins and their annotated locations for NP_001264396.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

Source sequence(s)

BU228669, BX929949, CF256811, CR353858

UniProtKB/TrEMBL

A0A1D5PED8

Related

ENSGALP00010022293.1, ENSGALT00010038524.1

Conserved Domains (1) summary

smart00658
Location:2 → 119

RPOL8c; RNA polymerase subunit 8
NM_001277468.1 → NP_001264397.1 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) lacks two alternate exons, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.

Source sequence(s)

BU228669, CF256811, CR353858

UniProtKB/TrEMBL

A0A1D5PCT2

Related

ENSGALP00010022295.1, ENSGALT00010038530.1

Conserved Domains (1) summary

cl02716
Location:2 → 52

RNA_pol_Rpb8; RNA polymerase Rpb8

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

15646550..15648498 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

15440283..15442231 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)