U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MME membrane metalloendopeptidase [ Gallus gallus (chicken) ]

Gene ID: 425031, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Symbol
MMEprovided by CGNC
Full Name
membrane metalloendopeptidaseprovided by CGNC
Primary source
CGNC:7860
See related
Ensembl:ENSGALG00010001385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MME in Genome Data Viewer
Location:
chromosome: 9
Exon count:
25
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (22770656..22809660, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (22556007..22595014, complement)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene phospholipase C eta 1 Neighboring gene uncharacterized LOC101748152 Neighboring gene G protein-coupled receptor 149 Neighboring gene uncharacterized LOC121111514 Neighboring gene DEAH-box helicase 36

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The chick embryo appears as a natural model for research in beta-amyloid precursor protein processing. Carrodeguas JA, et al. Neuroscience, 2005. PMID 16039787
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neprilysin
Names
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
neutral endopeptidase
NP_001004412.1
NP_001383129.1
NP_001383130.1
NP_001383131.1
NP_001383132.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004412.2 → NP_001004412.1  neprilysin

    See identical proteins and their annotated locations for NP_001004412.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0X882, Q67BJ2
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  2. NM_001396200.1 → NP_001383129.1  neprilysin

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0X882, Q67BJ2
    Related
    ENSGALP00010001668.1, ENSGALT00010003206.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  3. NM_001396201.1 → NP_001383130.1  neprilysin

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0X882, Q67BJ2
    Related
    ENSGALP00010001693.1, ENSGALT00010003236.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  4. NM_001396202.1 → NP_001383131.1  neprilysin

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0X882, Q67BJ2
    Related
    ENSGALP00010001740.1, ENSGALT00010003282.1
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

  5. NM_001396203.1 → NP_001383132.1  neprilysin

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000240
    UniProtKB/TrEMBL
    A0A8V0X882, Q67BJ2
    Conserved Domains (1) summary
    cd08662
    Location:79 → 748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    22770656..22809660 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    22556007..22595014 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.