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CG6656 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42576, updated on 9-Dec-2024

Summary

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Official Symbol
CG6656provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038912
Locus tag
Dmel_CG6656
See related
AllianceGenome:FB:FBgn0038912
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6656
Summary
Predicted to enable acid phosphatase activity. Predicted to be located in extracellular exosome and nucleus. Is expressed in adult head; eye; and photoreceptor neurons. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Orthologous to human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6656 in Genome Data Viewer
Location:
93F14-93F14; 3-73 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21875293..21877788)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17701015..17703510)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45046 Neighboring gene uncharacterized protein Neighboring gene delta-1-Pyrroline-5-carboxylate dehydrogenase 2 Neighboring gene uncharacterized protein Neighboring gene female-specific independent of transformer

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity. Vichas A, et al. J Cell Biol, 2015 Dec 7. PMID 26644515, Free PMC Article
  2. CULD is required for rhodopsin and TRPL channel endocytic trafficking and survival of photoreceptor cells. Xu Y, et al. J Cell Sci, 2016 Jan 15. PMID 26598556, Free PMC Article
  3. Vitamin A deficiency affects gene expression in the Drosophila melanogaster head. Dewett D, et al. G3 (Bethesda), 2021 Oct 19. PMID 34849795, Free PMC Article
  4. Isolation of mRNA from specific tissues of Drosophila by mRNA tagging. Yang Z, et al. Nucleic Acids Res, 2005 Oct 4. PMID 16204451, Free PMC Article
  5. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. Xu H, et al. EMBO J, 2004 Feb 25. PMID 14963491, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables acid phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6656-PA
NP_650991.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    21875293..21877788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142734.2 → NP_650991.1  uncharacterized protein Dmel_CG6656 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650991.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VD68
    Related
    FBpp0083537
    Conserved Domains (1) summary
    cd07061
    Location:41 → 344
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VD68 Q9VD68

Gene LinkOut

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