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Fadd - Fas-associated death domain

Enables CARD domain binding activity. Involved in several processes, including defense response to bacterium; positive regulation of defense response to virus by host; and sperm individualization. Located in cytoplasm. Is expressed in adult Malpighian tubule. Human ortholog(s) of this gene implicated in leukemia and primary immunodeficiency disease. Orthologous to human FADD (Fas associated via death domain). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa