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FRMD4B FERM domain containing 4B [ Gallus gallus (chicken) ]

Gene ID: 426071, updated on 17-Aug-2024

Summary

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Official Symbol
FRMD4Bprovided by CGNC
Official Full Name
FERM domain containing 4Bprovided by CGNC
Primary source
CGNC:52665
See related
Ensembl:ENSGALG00010020127
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See FRMD4B in Genome Data Viewer
Location:
chromosome: 12
Exon count:
27
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (15528967..15629445, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (15562606..15663060, complement)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 5 Neighboring gene leiomodin 3 Neighboring gene uncharacterized LOC121106660 Neighboring gene melanocyte inducing transcription factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in establishment of epithelial cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
FERM domain-containing protein 4B
Names
GRP1-binding protein GRSP1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15528967..15629445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646786.2 → XP_040502720.1  FERM domain-containing protein 4B isoform X7

    UniProtKB/TrEMBL
    A0A8V0Z672
    Related
    ENSGALP00010028743.1, ENSGALT00010048652.1
    Conserved Domains (3) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  2. XM_423748.8 → XP_423748.2  FERM domain-containing protein 4B isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z672, A0A8V0ZCX4
    Related
    ENSGALP00010028736.1, ENSGALT00010048645.1
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  3. XM_004944685.5 → XP_004944742.1  FERM domain-containing protein 4B isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z672
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  4. XM_040646788.2 → XP_040502722.1  FERM domain-containing protein 4B isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Related
    ENSGALP00010028723.1, ENSGALT00010048632.1
    Conserved Domains (2) summary
    smart00295
    Location:85 → 134
    B41; Band 4.1 homologues
    cd13191
    Location:130 → 240
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

  5. XM_015293247.4 → XP_015148733.1  FERM domain-containing protein 4B isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Related
    ENSGALP00010028718.1, ENSGALT00010048627.1
    Conserved Domains (4) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:341 → 474
    DUF3338; Domain of unknown function (DUF3338)

  6. XM_015293242.4 → XP_015148728.1  FERM domain-containing protein 4B isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (4) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:341 → 474
    DUF3338; Domain of unknown function (DUF3338)

  7. XM_015293240.4 → XP_015148726.1  FERM domain-containing protein 4B isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  8. XM_015293239.4 → XP_015148725.1  FERM domain-containing protein 4B isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (3) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  9. XM_040646785.2 → XP_040502719.1  FERM domain-containing protein 4B isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (3) summary
    smart00295
    Location:54 → 254
    B41; Band 4.1 homologues
    cd13191
    Location:250 → 360
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:51 → 139
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  10. XM_040646787.1 → XP_040502721.1  FERM domain-containing protein 4B isoform X9

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Conserved Domains (3) summary
    cd13191
    Location:89 → 199
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    pfam00373
    Location:27 → 93
    FERM_M; FERM central domain
    pfam11819
    Location:228 → 361
    DUF3338; Domain of unknown function (DUF3338)

  11. XM_015293245.4 → XP_015148731.2  FERM domain-containing protein 4B isoform X8

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Conserved Domains (2) summary
    smart00295
    Location:85 → 134
    B41; Band 4.1 homologues
    cd13191
    Location:130 → 240
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15562606..15663060 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682472.2 → XP_040538406.1  FERM domain-containing protein 4B isoform X7

    UniProtKB/TrEMBL
    A0A8V0Z672
    Conserved Domains (3) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  2. XM_040682469.2 → XP_040538403.1  FERM domain-containing protein 4B isoform X5

    UniProtKB/TrEMBL
    A0A8V0Z672, A0A8V0ZCX4
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  3. XM_040682468.2 → XP_040538402.1  FERM domain-containing protein 4B isoform X4

    UniProtKB/TrEMBL
    A0A8V0Z672
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  4. XM_040682475.2 → XP_040538409.1  FERM domain-containing protein 4B isoform X10

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Conserved Domains (2) summary
    smart00295
    Location:85 → 134
    B41; Band 4.1 homologues
    cd13191
    Location:130 → 240
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)

  5. XM_040682470.2 → XP_040538404.1  FERM domain-containing protein 4B isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (4) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:341 → 474
    DUF3338; Domain of unknown function (DUF3338)

  6. XM_040682471.2 → XP_040538405.1  FERM domain-containing protein 4B isoform X6

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (4) summary
    smart00295
    Location:6 → 206
    B41; Band 4.1 homologues
    cd13191
    Location:202 → 312
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:3 → 91
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:341 → 474
    DUF3338; Domain of unknown function (DUF3338)

  7. XM_040682466.2 → XP_040538400.1  FERM domain-containing protein 4B isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (4) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)
    pfam11819
    Location:395 → 528
    DUF3338; Domain of unknown function (DUF3338)

  8. XM_040682465.2 → XP_040538399.1  FERM domain-containing protein 4B isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (3) summary
    smart00295
    Location:60 → 260
    B41; Band 4.1 homologues
    cd13191
    Location:256 → 366
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:57 → 145
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  9. XM_040682467.2 → XP_040538401.1  FERM domain-containing protein 4B isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZJE2
    Conserved Domains (3) summary
    smart00295
    Location:54 → 254
    B41; Band 4.1 homologues
    cd13191
    Location:250 → 360
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    cd17200
    Location:51 → 139
    FERM_F1_FRMD4B; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in FERM domain-containing protein 4B (FRMD4B)

  10. XM_040682474.1 → XP_040538408.1  FERM domain-containing protein 4B isoform X9

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Conserved Domains (3) summary
    cd13191
    Location:89 → 199
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
    pfam00373
    Location:27 → 93
    FERM_M; FERM central domain
    pfam11819
    Location:228 → 361
    DUF3338; Domain of unknown function (DUF3338)

  11. XM_040682473.2 → XP_040538407.1  FERM domain-containing protein 4B isoform X8

    UniProtKB/TrEMBL
    A0A8V0ZJE7
    Conserved Domains (2) summary
    smart00295
    Location:85 → 134
    B41; Band 4.1 homologues
    cd13191
    Location:130 → 240
    FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
Nucleotide Protein Strain
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