U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CAH8 Carbonic anhydrase 8 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42625, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
CAH8provided by FlyBase
Official Full Name
Carbonic anhydrase 8provided by FlyBase
Primary source
FLYBASE:FBgn0038956
Locus tag
Dmel_CG5379
See related
AllianceGenome:FB:FBgn0038956
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5379; Dmel\CG5379
Summary
Predicted to enable carbonate dehydratase activity. Predicted to be active in cytoplasm. Is expressed in adult heart. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CAH8 in Genome Data Viewer
Location:
94A11-94A11; 3-74 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22386489..22389714, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18212211..18215436, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Glycerol-3-phosphate dehydrogenase 3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene transfer RNA:Serine-GCT 2-3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Carbonic anhydrases and anion transport in mosquito midgut pH regulation. Linser PJ, et al. J Exp Biol, 2009 Jun. PMID 19448076, Free PMC Article
  2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbonate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
carbonic anhydrase 8
Names
CAH8-PA
CAH8-PB
CG5379-PA
CG5379-PB
NP_001262833.1
NP_651033.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    22386489..22389714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275904.1 → NP_001262833.1  carbonic anhydrase 8, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262833.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V4S9, Q9VD19
    Conserved Domains (1) summary
    smart01057
    Location:31 → 281
    Carb_anhydrase; Eukaryotic-type carbonic anhydrase

  2. NM_142776.4 → NP_651033.2  carbonic anhydrase 8, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651033.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V4S9, Q9VD19
    Conserved Domains (1) summary
    smart01057
    Location:31 → 281
    Carb_anhydrase; Eukaryotic-type carbonic anhydrase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V4S9 Q4V4S9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools