lqfR liquid facets-Related [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: lqfRprovided by FlyBase
Official Full Name: liquid facets-Relatedprovided by FlyBase
Primary source: FLYBASE:FBgn0261279
Locus tag: Dmel_CG42250
See related: AllianceGenome:FB:FBgn0261279
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG13853; CG13854; CG31170; CG31285; CG42250; Dmel\CG42250; dTel2; epsin; Epsin; epsin-like; epsin02; epsinR; l(3)03685; l(3)A9; l(3)dsl-9; l(3)dsl9; l(3)SG62; l(3)XII-10; Lqfr; LqfR; Tel2; XII-10
Old locus tag: Dmel_CG31170; Dmel_CG31285
Summary: Predicted to enable clathrin binding activity and phospholipid binding activity. Involved in oogenesis. Located in early endosome; nucleus; and trans-Golgi network. Is expressed in several structures, including embryonic/larval midgut primordium; germline cell; gland; gut section; and imaginal disc. Orthologous to human CLINT1 (clathrin interactor 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (22411301..22419051)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (18237023..18244773)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

At least one of the functions of Drosophila Tel2/EpsinR is regulation of Wingless signaling.
Title: Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signaling.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables clathrin binding	IBA Inferred from Biological aspect of Ancestor more info
enables phospholipid binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in endocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in oogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
part_of clathrin vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in early endosome	IDA Inferred from Direct Assay more info	PubMed
is_active_in endosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	IDA Inferred from Direct Assay more info	PubMed

Names: CG42250-PC; CG42250-PD; EpsinR; epsin-2; epsin-like; lethal (3) SG62; liquid facet related; liquid facets related; liquid-facets related; lqfR-PC; lqfR-PD

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The following sections contain reference sequences that belong to a specific genome build. Explain