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ADGRA2 adhesion G protein-coupled receptor A2 [ Gallus gallus (chicken) ]

Gene ID: 426771, updated on 17-Aug-2024

Summary

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Symbol
ADGRA2provided by CGNC
Full Name
adhesion G protein-coupled receptor A2provided by CGNC
Primary source
CGNC:2258
See related
Ensembl:ENSGALG00010021026
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GPR124
Orthologs
human mouse all
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Genomic context

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See ADGRA2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 22 NC_052553.1 (2367563..2386739)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 22 NC_052594.1 (2414840..2434010)

Chromosome 22 - NC_052553.1Genomic Context describing neighboring genes Neighboring gene ER lipid raft associated 2 Neighboring gene proline synthetase cotranscribed homolog (bacterial) Neighboring gene uncharacterized LOC124417353 Neighboring gene RAB11 family interacting protein 1 Neighboring gene BRF2 RNA polymerase III transcription initiation factor subunit Neighboring gene prolactin releasing hormone receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Wnt signalosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adhesion G protein-coupled receptor A2
Names
G protein-coupled receptor 124

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052553.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2367563..2386739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015297425.4 → XP_015152911.3  adhesion G protein-coupled receptor A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZGV0, A0A8V0ZGV6
    Conserved Domains (9) summary
    smart00410
    Location:181 → 270
    IG_like; Immunoglobulin like
    PLN00113
    Location:29 → 118
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:35 → 58
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1069 → 1172
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:684 → 709
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:276 → 343
    HRM; Hormone receptor domain
    cl02559
    Location:624 → 673
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:117 → 164
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:683 → 988
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_015297426.4 → XP_015152912.3  adhesion G protein-coupled receptor A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZGV0, A0A8V0ZGV6
    Related
    ENSGALP00010030062.1, ENSGALT00010050871.1
    Conserved Domains (9) summary
    smart00410
    Location:181 → 270
    IG_like; Immunoglobulin like
    PLN00113
    Location:29 → 118
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:35 → 58
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1069 → 1172
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:684 → 709
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:276 → 343
    HRM; Hormone receptor domain
    cl02559
    Location:624 → 673
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:117 → 164
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:683 → 988
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_015297424.4 → XP_015152910.3  adhesion G protein-coupled receptor A2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z9U4, A0A8V0ZGZ5
    Related
    ENSGALP00010030061.1, ENSGALT00010050870.1
    Conserved Domains (9) summary
    smart00409
    Location:243 → 332
    IG; Immunoglobulin
    PLN00113
    Location:91 → 180
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:75 → 96
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1131 → 1234
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:746 → 771
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:338 → 405
    HRM; Hormone receptor domain
    cl02559
    Location:686 → 735
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:179 → 226
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:745 → 1050
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_004947584.5 → XP_004947641.4  adhesion G protein-coupled receptor A2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZGV0
    Conserved Domains (7) summary
    TIGR00864
    Location:13 → 80
    PCC; polycystin cation channel protein
    smart00409
    Location:107 → 196
    IG; Immunoglobulin
    cl21589
    Location:995 → 1098
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:610 → 635
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:202 → 269
    HRM; Hormone receptor domain
    cl02559
    Location:550 → 599
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:609 → 914
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052594.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2414840..2434010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040689301.2 → XP_040545235.1  adhesion G protein-coupled receptor A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZGV0
    Conserved Domains (9) summary
    smart00410
    Location:181 → 270
    IG_like; Immunoglobulin like
    PLN00113
    Location:29 → 118
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:35 → 58
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1069 → 1172
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:684 → 709
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:276 → 343
    HRM; Hormone receptor domain
    cl02559
    Location:624 → 673
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:117 → 164
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:683 → 988
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_040689302.2 → XP_040545236.1  adhesion G protein-coupled receptor A2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZGV0
    Conserved Domains (9) summary
    smart00410
    Location:181 → 270
    IG_like; Immunoglobulin like
    PLN00113
    Location:29 → 118
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:35 → 58
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1069 → 1172
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:684 → 709
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:276 → 343
    HRM; Hormone receptor domain
    cl02559
    Location:624 → 673
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:117 → 164
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:683 → 988
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_040689300.2 → XP_040545234.1  adhesion G protein-coupled receptor A2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z9U4
    Conserved Domains (9) summary
    smart00409
    Location:243 → 332
    IG; Immunoglobulin
    PLN00113
    Location:91 → 180
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:75 → 96
    LRR_1; leucine-rich repeat [structural motif]
    cl21589
    Location:1131 → 1234
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:747 → 771
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:338 → 405
    HRM; Hormone receptor domain
    cl02559
    Location:686 → 735
    GPS; GPCR proteolysis site, GPS, motif
    cl15307
    Location:179 → 226
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl28897
    Location:745 → 1050
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_040689304.2 → XP_040545238.1  adhesion G protein-coupled receptor A2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZGV0
    Conserved Domains (7) summary
    TIGR00864
    Location:13 → 80
    PCC; polycystin cation channel protein
    smart00410
    Location:107 → 196
    IG_like; Immunoglobulin like
    cl21589
    Location:995 → 1098
    Relaxase; Relaxase/Mobilisation nuclease domain
    cd14964
    Location:610 → 635
    7tm_GPCRs; TM helix 1 [structural motif]
    cl02422
    Location:202 → 269
    HRM; Hormone receptor domain
    cl02559
    Location:550 → 599
    GPS; GPCR proteolysis site, GPS, motif
    cl28897
    Location:609 → 914
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
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