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wfs1 - wolfram syndrome 1

Predicted to enable ubiquitin protein ligase binding activity. Involved in adult locomotory behavior and negative regulation of gene expression. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head and organism. Used to study Wolfram syndrome 1. Human ortholog(s) of this gene implicated in several diseases, including Wolfram syndrome (multiple); auditory system disease (multiple); cataract 41; diabetes mellitus (multiple); and optic atrophy (multiple). Orthologous to human WFS1 (wolframin ER transmembrane glycoprotein). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to wfs1

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Species Gene Architecture aa