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CG6660 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42708, updated on 9-Dec-2024

Summary

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Official Symbol
CG6660provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039030
Locus tag
Dmel_CG6660
See related
AllianceGenome:FB:FBgn0039030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6660
Summary
Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1) and ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG6660 in Genome Data Viewer
Location:
94D3-94D4; 3-77 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22923352..22924525)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (18749074..18750247)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43846 Neighboring gene uncharacterized protein Neighboring gene klingon Neighboring gene long non-coding RNA:CR46088 Neighboring gene long non-coding RNA:CR43655

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Drosophila cell adhesion molecule klingon is required for long-term memory formation and is regulated by Notch. Matsuno M, et al. Proc Natl Acad Sci U S A, 2009 Jan 6. PMID 19104051, Free PMC Article
  2. Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system. Parvy JP, et al. PLoS Genet, 2012. PMID 22956916, Free PMC Article
  3. A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytes. Szafer-Glusman E, et al. Curr Biol, 2008 Sep 23. PMID 18804373, Free PMC Article
  4. The fatty acid elongase NOA is necessary for viability and has a somatic role in Drosophila sperm development. Jung A, et al. J Cell Sci, 2007 Aug 15. PMID 17666430
  5. A fatty acid anabolic pathway in specialized-cells sustains a remote signal that controls egg activation in Drosophila. Poidevin M, et al. PLoS Genet, 2024 Mar. PMID 38483976, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables fatty acid elongase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fatty acid elongase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid elongation, monounsaturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid elongation, polyunsaturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid elongation, saturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sphingolipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in very long-chain fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6660-PA
NP_651104.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    22923352..22924525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142847.2 → NP_651104.1  uncharacterized protein Dmel_CG6660 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651104.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2J644, Q9VCT3
    Related
    FBpp0083731
    Conserved Domains (1) summary
    pfam01151
    Location:25 → 265
    ELO; GNS1/SUR4 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VCT3 Q9VCT3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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