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RNF20 ring finger protein 20 [ Gallus gallus (chicken) ]

Gene ID: 427310, updated on 3-Dec-2024

Summary

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Symbol
RNF20provided by CGNC
Full Name
ring finger protein 20provided by CGNC
Primary source
CGNC:53045
See related
Ensembl:ENSGALG00010005549
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
BRE1A
Orthologs
human mouse all
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Genomic context

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See RNF20 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
20
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (65770066..65788473, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (65770066..65788473, complement)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417556 Neighboring gene glutamate ionotropic receptor NMDA type subunit 3A Neighboring gene transmembrane protein 246 Neighboring gene uncharacterized LOC107052401 Neighboring gene aldolase, fructose-bisphosphate B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity. Ma MK, et al. PLoS Genet, 2011 Jul. PMID 21811414, Free PMC Article
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that HS4 insulator element recruits the E3 ligase RNF20/BRE1A to mediate H2B mono-ubiquitination (H2Bub1) at this insulator.
    Title: Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of HULC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase BRE1A
Names
BRE1-A
RING-type E3 ubiquitin transferase BRE1A
ring finger protein 20, E3 ubiquitin protein ligase
NP_001026605.2
XP_015136088.1
XP_015136089.1
XP_015136090.1
XP_040511504.2
XP_046761353.1
XP_046761354.1
XP_046791121.1
XP_046791122.1
XP_046791123.1
XP_046791124.1
XP_046791125.1
XP_046791126.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031434.2 → NP_001026605.2  E3 ubiquitin-protein ligase BRE1A

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000095
    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6
    Conserved Domains (3) summary
    PTZ00121
    Location:322 → 907
    PTZ00121; MAEBL; Provisional
    COG1196
    Location:45 → 394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd16704
    Location:929 → 974
    RING-HC_RNF20_like; RING finger, HC subclass, found in RING finger protein RNF20, RNF40, and similar proteins

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    65770066..65788473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015280602.4 → XP_015136088.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6
    Related
    ENSGALP00010007841.1, ENSGALT00010013279.1
    Conserved Domains (3) summary
    PTZ00121
    Location:322 → 907
    PTZ00121; MAEBL; Provisional
    COG1196
    Location:45 → 394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd16704
    Location:929 → 974
    RING-HC_RNF20_like; RING finger, HC subclass, found in RING finger protein RNF20, RNF40, and similar proteins

  2. XM_046905398.1 → XP_046761354.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  3. XM_015280603.4 → XP_015136089.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6
    Conserved Domains (3) summary
    PTZ00121
    Location:322 → 907
    PTZ00121; MAEBL; Provisional
    COG1196
    Location:45 → 394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd16704
    Location:929 → 974
    RING-HC_RNF20_like; RING finger, HC subclass, found in RING finger protein RNF20, RNF40, and similar proteins

  4. XM_046905397.1 → XP_046761353.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  5. XM_040655570.2 → XP_040511504.2  E3 ubiquitin-protein ligase BRE1A isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    A0A8V0XPM8
    Related
    ENSGALP00010007838.1, ENSGALT00010013276.1

  6. XM_015280604.4 → XP_015136090.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6
    Conserved Domains (3) summary
    PTZ00121
    Location:322 → 907
    PTZ00121; MAEBL; Provisional
    COG1196
    Location:45 → 394
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd16704
    Location:929 → 974
    RING-HC_RNF20_like; RING finger, HC subclass, found in RING finger protein RNF20, RNF40, and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    65770066..65788473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046935166.1 → XP_046791122.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  2. XM_046935170.1 → XP_046791126.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  3. XM_046935168.1 → XP_046791124.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  4. XM_046935169.1 → XP_046791125.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6

  5. XM_046935165.1 → XP_046791121.1  E3 ubiquitin-protein ligase BRE1A isoform X1

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    A0A8V0XPM8

  6. XM_046935167.1 → XP_046791123.1  E3 ubiquitin-protein ligase BRE1A isoform X2

    UniProtKB/Swiss-Prot
    Q5ZLS3
    UniProtKB/TrEMBL
    F1N9A6
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZLS3.1 GenPept UniProtKB/Swiss-Prot:Q5ZLS3

Gene LinkOut

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