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hh - hedgehog

Enables morphogen activity and patched binding activity. Involved in several processes, including imaginal disc morphogenesis; open tracheal system development; and regionalization. Located in several cellular components, including cytoplasmic vesicle; extracellular space; and nucleus. Is expressed in several structures, including gut section; imaginal disc; imaginal disc posterior compartment; segment; and somatic precursor cell. Used to study primary bacterial infectious disease. Human ortholog(s) of this gene implicated in several diseases, including 46,XY sex reversal (multiple); Hirschsprung's disease; bone development disease (multiple); holoprosencephaly (multiple); and hypoplastic or aplastic tibia with polydactyly. Orthologous to human IHH (Indian hedgehog signaling molecule); DHH (desert hedgehog signaling molecule); and SHH (sonic hedgehog signaling molecule). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to hh

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Species Gene Architecture aa