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bb8 - big bubble 8

Enables glutamate dehydrogenase (NAD+) activity. Involved in glutamate catabolic process and negative regulation of mitochondrial fission. Located in mitochondrion. Is expressed in adult head; elongation stage spermatid; primary spermatocyte; spermatid cyst; and spermatozoon. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; and hypoglycemia. Orthologous to human GLUD1 (glutamate dehydrogenase 1). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to bb8

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Species Gene Architecture aa