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ADORA2A adenosine A2a receptor [ Gallus gallus (chicken) ]

Gene ID: 427705, updated on 17-Aug-2024

Summary

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Official Symbol
ADORA2Aprovided by CGNC
Official Full Name
adenosine A2a receptorprovided by CGNC
Primary source
CGNC:5013
See related
Ensembl:ENSGALG00010026448
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ADORA2A in Genome Data Viewer
Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (8481619..8510505, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (8492369..8521227, complement)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein D3 polypeptide Neighboring gene guanylyl cyclase domain containing 1 Neighboring gene beta-ureidopropionase 1 Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like Neighboring gene BCR activator of RhoGEF and GTPase Neighboring gene RAB36, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of A1 adenosine receptors in the developing avian retina: in vivo modulation by A(2A) receptors and endogenous adenosine. Brito R, et al. J Neurochem, 2012 Oct. PMID 22862679
  2. Modulation of A1 adenosine receptor expression by cell aggregation and long-term activation of A2a receptors in cultures of avian retinal cells: involvement of the cyclic AMP/PKA pathway. Pereira MR, et al. J Neurochem, 2010 May. PMID 20163523
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long-term treatment with A2A adenosine receptors in developing retina modulate expression of A1 adenosine receptors.
    Title: Expression of A1 adenosine receptors in the developing avian retina: in vivo modulation by A(2A) receptors and endogenous adenosine.
  2. adenosine A2a receptor and the cAMP-dependent protein kinase pathway are involved in the regulation of adenosine A1 receptor expression during retinal development
    Title: Modulation of A1 adenosine receptor expression by cell aggregation and long-term activation of A2a receptors in cultures of avian retinal cells: involvement of the cyclic AMP/PKA pathway.
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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled adenosine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled adenosine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenosine receptor A2a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8481619..8510505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040648132.2 → XP_040504066.1  adenosine receptor A2a isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADB5
    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_040648131.2 → XP_040504065.1  adenosine receptor A2a isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADB5
    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_040648130.2 → XP_040504064.1  adenosine receptor A2a isoform X1

    UniProtKB/TrEMBL
    A0A8V1ADB5
    Related
    ENSGALP00010039497.1, ENSGALT00010064309.1
    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_046901333.1 → XP_046757289.1  adenosine receptor A2a isoform X2

RNA

  1. XR_005840036.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    8492369..8521227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040684943.2 → XP_040540877.1  adenosine receptor A2a isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_040684942.2 → XP_040540876.1  adenosine receptor A2a isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_040684941.2 → XP_040540875.1  adenosine receptor A2a isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:14 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:13 → 308
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_046928480.1 → XP_046784436.1  adenosine receptor A2a isoform X2

RNA

  1. XR_005854444.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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