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Ugt303B3 UDP-glycosyltransferase family 303 member B3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42774, updated on 9-Dec-2024

Summary

Official Symbol
Ugt303B3provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 303 member B3provided by FlyBase
Primary source
FLYBASE:FBgn0039085
Locus tag
Dmel_CG10170
See related
AllianceGenome:FB:FBgn0039085
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10170; Dmel\CG10170; UGT303B3
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in embryonic small intestine and embryonic/larval midgut. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Ugt303B3 in Genome Data Viewer
Location:
95A1-95A1; 3-80 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23532945..23534767, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19358667..19360489, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene UDP-glycosyltransferase family 303 member B1 Neighboring gene UDP-glycosyltransferase family 303 member B2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
UDP-glycosyltransferase family 303 member B3
Names
CG10170-PA
Ugt303B3-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    23532945..23534767 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142895.3NP_651152.1  UDP-glycosyltransferase family 303 member B3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651152.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V5U2, Q9VCL5
    Related
    FBpp0083812
    Conserved Domains (1) summary
    PHA03392
    Location:7466
    egt; ecdysteroid UDP-glucosyltransferase; Provisional