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GUSB glucuronidase beta [ Gallus gallus (chicken) ]

Gene ID: 427823, updated on 3-Dec-2024

Summary

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Symbol
GUSBprovided by CGNC
Full Name
glucuronidase betaprovided by CGNC
Primary source
CGNC:53202
See related
Ensembl:ENSGALG00010029663
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
beta-glucuronidase
Orthologs
human mouse all
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Genomic context

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See GUSB in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (5407584..5420023, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (5143763..5156193, complement)

Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 2 Neighboring gene vitamin K epoxide reductase complex subunit 1 like 1 Neighboring gene tyrosylprotein sulfotransferase 1 Neighboring gene CGRP receptor component Neighboring gene argininosuccinate lyase Neighboring gene argininosuccinate lyase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Membrane receptor-initiated signaling in 1,25(OH)2D3-stimulated calcium uptake in intestinal epithelial cells. Khanal RC, et al. J Cell Biochem, 2008 Nov 1. PMID 18773429
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. 1,25(OH)2D3 and PTH increase calcium uptake by stimulating the PKA pathway to release beta-glucuronidase, which in turn activates TRPV6.
    Title: Membrane receptor-initiated signaling in 1,25(OH)2D3-stimulated calcium uptake in intestinal epithelial cells.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-glucuronidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-glucuronidase
NP_001034405.1
XP_015151296.1
XP_046786134.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039316.2 → NP_001034405.1  beta-glucuronidase precursor

    See identical proteins and their annotated locations for NP_001034405.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ720880
    UniProtKB/TrEMBL
    A0A8V1AN71, Q5ZIA4
    Related
    ENSGALP00010044406.1, ENSGALT00010071716.1
    Conserved Domains (4) summary
    PRK10150
    Location:37 → 641
    PRK10150; beta-D-glucuronidase; Provisional
    pfam00703
    Location:236 → 337
    Glyco_hydro_2; Glycosyl hydrolases family 2
    pfam02836
    Location:339 → 641
    Glyco_hydro_2_C; Glycosyl hydrolases family 2, TIM barrel domain
    pfam02837
    Location:46 → 234
    Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5407584..5420023 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015295810.4 → XP_015151296.1  beta-glucuronidase isoform X1

    UniProtKB/TrEMBL
    A0A1L1RSD2, A0A8V1AN71
    Related
    ENSGALP00010044408.1, ENSGALT00010071718.1
    Conserved Domains (4) summary
    PRK10150
    Location:37 → 641
    PRK10150; beta-D-glucuronidase; Provisional
    pfam00703
    Location:236 → 337
    Glyco_hydro_2; Glycosyl hydrolases family 2
    pfam02836
    Location:339 → 641
    Glyco_hydro_2_C; Glycosyl hydrolases family 2, TIM barrel domain
    pfam02837
    Location:46 → 234
    Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    5143763..5156193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046930178.1 → XP_046786134.1  beta-glucuronidase isoform X1

    UniProtKB/TrEMBL
    A0A8V1AN71
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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