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Ndc1 Nuclear division cycle 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42825, updated on 4-Jan-2025

Summary

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Official Symbol
Ndc1provided by FlyBase
Official Full Name
Nuclear division cycle 1provided by FlyBase
Primary source
FLYBASE:FBgn0039125
Locus tag
Dmel_CG5857
See related
AllianceGenome:FB:FBgn0039125
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5857; Dmel\CG5857; ndc1; NDC1
Summary
Predicted to enable protein-macromolecule adaptor activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nuclear pore complex assembly. Located in endomembrane system. Is expressed in adult head and organism. Orthologous to human NDC1 (NDC1 transmembrane nucleoporin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Ndc1 in Genome Data Viewer
Location:
95C12-95C13; 3-81 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23924399..23926436)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19750121..19752158)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene six-banded Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Regulatory particle triple-A ATPase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Topology of yeast Ndc1p: predictions for the human NDC1/NET3 homologue. Lau CK, et al. Anat Rec A Discov Mol Cell Evol Biol, 2006 Jul. PMID 16779818, Free PMC Article
  2. Identification of potential pathways and biomarkers linked to progression in ALS. Huber RG, et al. Ann Clin Transl Neurol, 2023 Feb. PMID 36533811, Free PMC Article
  3. Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis. Hampoelz B, et al. Cell, 2019 Oct 17. PMID 31626769, Free PMC Article
  4. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. Raza Q, et al. PLoS Genet, 2019 Feb. PMID 30763317, Free PMC Article
  5. Comparative genomic evidence for a complete nuclear pore complex in the last eukaryotic common ancestor. Neumann N, et al. PLoS One, 2010 Oct 8. PMID 20949036, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of nuclear pore ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear pore complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in nuclear pore organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endomembrane system HDA PubMed 
part_of nuclear pore ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of nuclear pore transmembrane ring IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
nuclear division cycle 1
Names
CG5857-PA
Ndc1 ortholog
Ndc1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    23924399..23926436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142934.4 → NP_651191.1  nuclear division cycle 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651191.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q3YE69, Q9VCG4
    Related
    FBpp0083879
    Conserved Domains (1) summary
    pfam09531
    Location:63 → 571
    Ndc1_Nup; Nucleoporin protein Ndc1-Nup
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VCG4.1 Q9VCG4

Gene LinkOut

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