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CG12268 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42833, updated on 4-Jan-2025

Summary

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Official Symbol
CG12268provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039131
Locus tag
Dmel_CG12268
See related
AllianceGenome:FB:FBgn0039131
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12268
Summary
Predicted to enable alcohol-forming long-chain fatty acyl-CoA reductase activity and alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to be active in peroxisome. Is expressed in several structures, including adult head; embryonic Malpighian tubule tip cell; embryonic hypopharynx; epithelium; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG12268 in Genome Data Viewer
Location:
95D1-95D1; 3-82 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23943628..23948424, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19769350..19774146, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Ribosomal protein S19b Neighboring gene uncharacterized protein Neighboring gene Glutamate dehydrogenase Neighboring gene Glutamyl-prolyl-tRNA synthetase Neighboring gene antisense RNA:CR46092 Neighboring gene Adaptor Protein complex 1, sigma subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
  2. Identification of circadian-clock-regulated enhancers and genes of Drosophila melanogaster by transposon mobilization and luciferase reporting of cyclical gene expression. Stempfl T, et al. Genetics, 2002 Feb. PMID 11861563, Free PMC Article
  3. Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Ghosh AC, et al. Elife, 2020 Oct 27. PMID 33107824, Free PMC Article
  4. A genomic analysis of Drosophila somatic sexual differentiation and its regulation. Arbeitman MN, et al. Development, 2004 May. PMID 15056610
  5. An inventory of peroxisomal proteins and pathways in Drosophila melanogaster. Faust JE, et al. Traffic, 2012 Oct. PMID 22758915, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12268-PA
CG12268-PB
CG12268-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    23943628..23948424 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176550.2 → NP_788727.1  uncharacterized protein Dmel_CG12268, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788727.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VCF6
    Related
    FBpp0083901
    Conserved Domains (3) summary
    cd09071
    Location:372 → 463
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:22 → 347
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:12 → 463
    PLN02996; fatty acyl-CoA reductase

  2. NM_142940.3 → NP_651197.1  uncharacterized protein Dmel_CG12268, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651197.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VCF6
    Related
    FBpp0083900
    Conserved Domains (3) summary
    cd09071
    Location:372 → 463
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:22 → 347
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:12 → 463
    PLN02996; fatty acyl-CoA reductase

  3. NM_001260343.1 → NP_001247272.1  uncharacterized protein Dmel_CG12268, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247272.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VCF6
    Conserved Domains (3) summary
    cd09071
    Location:372 → 463
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:22 → 347
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
    PLN02996
    Location:12 → 463
    PLN02996; fatty acyl-CoA reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VCF6 Q9VCF6

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