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Rab7 - Rab7

Predicted to enable GTPase activity. Involved in several processes, including T-tubule organization; endosomal transport; and vesicle fusion. Located in cell cortex and late endosome membrane. Is expressed in several structures, including adult ensheathing glial cell; brain; imaginal disc; mushroom body; and synaptic neuropil domain. Used to study Charcot-Marie-Tooth disease type 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa