LSm3 Like Sm 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: LSm3provided by FlyBase
Official Full Name: Like Sm 3provided by FlyBase
Primary source: FLYBASE:FBgn0051184
Locus tag: Dmel_CG31184
See related: AllianceGenome:FB:FBgn0051184
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:RE11655; CG31184; CG5926; Dmel\CG31184; Lsm3
Summary: Predicted to enable RNA binding activity. Involved in P-body assembly. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in head mesoderm; organism; and trunk mesoderm. Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (23996262..23997017)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (19821984..19822739)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in P-body assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in P-body assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in mRNA splicing, via spliceosome	IC Inferred by Curator more info	PubMed
involved_in mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of Lsm1-7-Pat1 complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in P-body	IBA Inferred from Biological aspect of Ancestor more info
part_of U4/U6 x U5 tri-snRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of U6 snRNP	IBA Inferred from Biological aspect of Ancestor more info
part_of U6 snRNP	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of catalytic step 2 spliceosome	HDA more info	PubMed
part_of catalytic step 2 spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of precatalytic spliceosome	HDA more info	PubMed
part_of precatalytic spliceosome	IBA Inferred from Biological aspect of Ancestor more info