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CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 [ Gallus gallus (chicken) ]

Gene ID: 428420, updated on 17-Aug-2024

Summary

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Symbol
CACNB2provided by CGNC
Full Name
calcium voltage-gated channel auxiliary subunit beta 2provided by CGNC
Primary source
CGNC:6517
See related
Ensembl:ENSGALG00010006083
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See CACNB2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (19021947..19251742, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (19052291..19281795, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene MAM and LDL receptor class A domain containing 1 Neighboring gene ADP ribosylation factor like GTPase 5B Neighboring gene NOP2/Sun RNA methyltransferase family member 6 Neighboring gene solute carrier family 39 member 12 Neighboring gene mannose receptor C-type 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuromuscular junction development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit beta-2
Names
calcium channel, voltage-dependent, beta 2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    19021947..19251742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015282014.4 → XP_015137500.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Related
    ENSGALP00010008581.1, ENSGALT00010014569.1
    Conserved Domains (5) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:534 → 596
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:464 → 576
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:234 → 414
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  2. XM_015282013.4 → XP_015137499.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Conserved Domains (5) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:535 → 597
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:465 → 577
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:234 → 414
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  3. XM_015282012.4 → XP_015137498.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XUB2, E1BZF6
    Related
    ENSGALP00010008579.1, ENSGALT00010014566.1
    Conserved Domains (4) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:572 → 634
    SF-CC1; splicing factor, CC1-like family
    pfam00625
    Location:272 → 452
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  4. XM_015282011.4 → XP_015137497.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Conserved Domains (4) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:573 → 635
    SF-CC1; splicing factor, CC1-like family
    pfam00625
    Location:272 → 452
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  5. XM_025148387.3 → XP_025004155.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X11

    Conserved Domains (2) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    cl17190
    Location:282 → 453
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  6. XM_040691860.2 → XP_040547794.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2U3E1, A0A8V0XX03
    Related
    ENSGALP00010008570.1, ENSGALT00010014553.1
    Conserved Domains (3) summary
    cd12040
    Location:52 → 120
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:439 → 552
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:230 → 401
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  7. XM_015282016.4 → XP_015137502.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (5) summary
    cd12040
    Location:52 → 120
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:521 → 583
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:451 → 563
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:220 → 400
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:12 → 53
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  8. XM_040691871.2 → XP_040547805.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X9

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (3) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:414 → 527
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:204 → 375
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  9. XM_425981.8 → XP_425981.4  voltage-dependent L-type calcium channel subunit beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0XX03
    Related
    ENSGALP00010008569.1, ENSGALT00010014552.1
    Conserved Domains (5) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:532 → 594
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:462 → 574
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:232 → 412
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:24 → 65
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  10. XM_015282015.4 → XP_015137501.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (5) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:533 → 595
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:463 → 575
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:232 → 412
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:24 → 65
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  11. XM_040691880.2 → XP_040547814.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X10

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (3) summary
    cd12040
    Location:2 → 70
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:390 → 503
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:180 → 351
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    19052291..19281795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040662934.2 → XP_040518868.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Conserved Domains (5) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:534 → 596
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:464 → 576
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:234 → 414
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  2. XM_040662933.2 → XP_040518867.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Conserved Domains (5) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:535 → 597
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:465 → 577
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:234 → 414
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  3. XM_040662932.2 → XP_040518866.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0XUB2, E1BZF6
    Conserved Domains (4) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:572 → 634
    SF-CC1; splicing factor, CC1-like family
    pfam00625
    Location:272 → 452
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  4. XM_040662931.2 → XP_040518865.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0XUB2
    Conserved Domains (4) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:573 → 635
    SF-CC1; splicing factor, CC1-like family
    pfam00625
    Location:272 → 452
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:64 → 105
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  5. XM_040662941.2 → XP_040518875.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X11

    Conserved Domains (2) summary
    cd12040
    Location:104 → 172
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    cl17190
    Location:282 → 453
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  6. XM_040662938.2 → XP_040518872.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2U3E1, A0A8V0XX03
    Conserved Domains (3) summary
    cd12040
    Location:52 → 120
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:439 → 552
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:230 → 401
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  7. XM_040662937.2 → XP_040518871.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X7

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (5) summary
    cd12040
    Location:52 → 120
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:521 → 583
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:451 → 563
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:220 → 400
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:12 → 53
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  8. XM_040662939.2 → XP_040518873.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X9

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (3) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:414 → 527
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:204 → 375
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  9. XM_040662936.2 → XP_040518870.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X6

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (5) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:532 → 594
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:462 → 574
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:232 → 412
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:24 → 65
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  10. XM_040662935.2 → XP_040518869.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (5) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    TIGR01622
    Location:533 → 595
    SF-CC1; splicing factor, CC1-like family
    TIGR01642
    Location:463 → 575
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00625
    Location:232 → 412
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:24 → 65
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal

  11. XM_040662940.2 → XP_040518874.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X10

    UniProtKB/TrEMBL
    A0A8V0XX03
    Conserved Domains (3) summary
    cd12040
    Location:2 → 70
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam12782
    Location:390 → 503
    Innate_immun; Invertebrate innate immunity transcript family
    cl17190
    Location:180 → 351
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
Nucleotide Protein Strain
Heading Accession and Version

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