jar - jaguar

Enables calmodulin binding activity and cytoskeletal protein binding activity. Involved in several processes, including cytoskeleton organization; embryonic development via the syncytial blastoderm; and germ cell development. Located in several cellular components, including germline ring canal; growth cone; and investment cone. Part of microtubule associated complex and myosin VI complex. Is expressed in several structures, including adult heart; anterior-posterior subdivision of organism; brain; follicle cell; and spermatozoon. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 22; autosomal recessive nonsyndromic deafness 37; ovarian cancer; and sensorineural hearing loss. Orthologous to human MYO6 (myosin VI). [provided by Alliance of Genome Resources, Dec 2024]

NCBI Orthologs

How was this calculated?