U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NPL N-acetylneuraminate pyruvate lyase [ Gallus gallus (chicken) ]

Gene ID: 429074, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Symbol
NPLprovided by CGNC
Full Name
N-acetylneuraminate pyruvate lyaseprovided by CGNC
Primary source
CGNC:3411
See related
Ensembl:ENSGALG00010011434
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NPL in Genome Data Viewer
Location:
chromosome: 8
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (7432545..7442239)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (7444451..7465132)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107053944 Neighboring gene small nucleolar RNA SNORD47 Neighboring gene small nucleolar RNA SNORD81 Neighboring gene heme binding protein 2 Neighboring gene microRNA 1618 Neighboring gene uncharacterized LOC121111370

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4-hydroxy-tetrahydrodipicolinate synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N-acetylneuraminate lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-acetylneuraminate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
N-acetylneuraminate lyase
Names
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
N-acetylneuraminic acid aldolase
NALase
sialate lyase
sialate-pyruvate lyase
sialic acid aldolase
sialic acid lyase
NP_001026731.2
XP_025008665.2
XP_040560658.1
XP_040560659.1
XP_040560660.1
XP_040560661.1
XP_040560663.1
XP_040560664.1
XP_046778913.1
XP_046778914.1
XP_046778915.1
XP_046778916.1
XP_046778917.1
XP_046778918.1
XP_046778919.1
XP_046778920.1
XP_046778921.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001031560.3 → NP_001026731.2  N-acetylneuraminate lyase

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000237
    UniProtKB/Swiss-Prot
    Q5ZKD4
    UniProtKB/TrEMBL
    A0A8V0YD78
    Related
    ENSGALP00010015615.1, ENSGALT00010027361.1
    Conserved Domains (1) summary
    cl21457
    Location:7 → 297
    TIM; TIM-like beta/alpha barrel domains

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    7432545..7442239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040704724.2 → XP_040560658.1  N-acetylneuraminate lyase isoform X1

    UniProtKB/Swiss-Prot
    Q5ZKD4
    Conserved Domains (1) summary
    cl21457
    Location:23 → 298
    TIM; TIM-like beta/alpha barrel domains

  2. XM_040704726.2 → XP_040560660.1  N-acetylneuraminate lyase isoform X4

    UniProtKB/Swiss-Prot
    Q5ZKD4
    Conserved Domains (1) summary
    cl21457
    Location:23 → 278
    TIM; TIM-like beta/alpha barrel domains

  3. XM_040704725.2 → XP_040560659.1  N-acetylneuraminate lyase isoform X2

    UniProtKB/Swiss-Prot
    Q5ZKD4
    Conserved Domains (1) summary
    cl21457
    Location:19 → 294
    TIM; TIM-like beta/alpha barrel domains

  4. XM_040704730.2 → XP_040560664.1  N-acetylneuraminate lyase isoform X5

    Conserved Domains (1) summary
    cl21457
    Location:31 → 248
    TIM; TIM-like beta/alpha barrel domains

  5. XM_040704729.1 → XP_040560663.1  N-acetylneuraminate lyase isoform X5

    Conserved Domains (1) summary
    cl21457
    Location:31 → 248
    TIM; TIM-like beta/alpha barrel domains

  6. XM_040704727.1 → XP_040560661.1  N-acetylneuraminate lyase isoform X5

    Conserved Domains (1) summary
    cl21457
    Location:31 → 248
    TIM; TIM-like beta/alpha barrel domains

  7. XM_025152897.2 → XP_025008665.2  N-acetylneuraminate lyase isoform X3

    UniProtKB/Swiss-Prot
    Q5ZKD4
    Conserved Domains (1) summary
    cl21457
    Location:13 → 288
    TIM; TIM-like beta/alpha barrel domains

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7444451..7465132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922957.1 → XP_046778913.1  N-acetylneuraminate lyase isoform X1

    UniProtKB/Swiss-Prot
    Q5ZKD4

  2. XM_046922962.1 → XP_046778918.1  N-acetylneuraminate lyase isoform X4

    UniProtKB/Swiss-Prot
    Q5ZKD4

  3. XM_046922960.1 → XP_046778916.1  N-acetylneuraminate lyase isoform X2

    UniProtKB/Swiss-Prot
    Q5ZKD4

  4. XM_046922958.1 → XP_046778914.1  N-acetylneuraminate lyase isoform X6

    UniProtKB/Swiss-Prot
    Q5ZKD4
    UniProtKB/TrEMBL
    A0A8V0YD78

  5. XM_046922959.1 → XP_046778915.1  N-acetylneuraminate lyase isoform X6

    UniProtKB/Swiss-Prot
    Q5ZKD4
    UniProtKB/TrEMBL
    A0A8V0YD78

  6. XM_046922964.1 → XP_046778920.1  N-acetylneuraminate lyase isoform X5

  7. XM_046922965.1 → XP_046778921.1  N-acetylneuraminate lyase isoform X5

  8. XM_046922963.1 → XP_046778919.1  N-acetylneuraminate lyase isoform X5

  9. XM_046922961.1 → XP_046778917.1  N-acetylneuraminate lyase isoform X3

    UniProtKB/Swiss-Prot
    Q5ZKD4
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZKD4.1 GenPept UniProtKB/Swiss-Prot:Q5ZKD4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.