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CG6980 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42955, updated on 9-Dec-2024

Summary

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Official Symbol
CG6980provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039228
Locus tag
Dmel_CG6980
See related
AllianceGenome:FB:FBgn0039228
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0140519.171; Dmel\CG6980
Summary
Predicted to be involved in axonemal dynein complex assembly and sperm axoneme assembly. Predicted to be active in centrosome and cytoplasm. Is expressed in dorsal sensory complex proper primordium; embryonic head sensory system; sensory nervous system primordium; and ventral sensory complex primordium. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alcohol dependence; drug dependence (multiple); nicotine dependence; and primary ciliary dyskinesia 45. Orthologous to human TTC12 (tetratricopeptide repeat domain 12). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG6980 in Genome Data Viewer
Location:
96A23-96A23; 3-85 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24807621..24808677)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20633343..20634399)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Ets96B Neighboring gene Uracil-DNA degrading factor Neighboring gene polybromo Neighboring gene lilipod Neighboring gene antisense RNA:CR46096 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular evolution of sex-biased genes in the Drosophila ananassae subgroup. Grath S, et al. BMC Evol Biol, 2009 Dec 16. PMID 20015359, Free PMC Article
  2. The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception. Nagy V, et al. Cell Cycle, 2015. PMID 25891934, Free PMC Article
  3. Genetic programs activated by proneural proteins in the developing Drosophila PNS. Reeves N, et al. Dev Cell, 2005 Mar. PMID 15737936
  4. Notch and Ras signaling pathway effector genes expressed in fusion competent and founder cells during Drosophila myogenesis. Artero R, et al. Development, 2003 Dec. PMID 14602676
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in axonemal dynein complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sperm axoneme assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6980-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24807621..24808677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143032.2 → NP_651289.1  uncharacterized protein Dmel_CG6980 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651289.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0AMK7, Q9VC34
    Related
    FBpp0084076
    Conserved Domains (3) summary
    sd00006
    Location:128 → 156
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:162 → 190
    TPR_1; Tetratricopeptide repeat
    pfam13414
    Location:127 → 190
    TPR_11; TPR repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VC34 Q9VC34

Gene LinkOut

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