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CycB3 Cyclin B3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42971, updated on 9-Dec-2024

Summary

Official Symbol
CycB3provided by FlyBase
Official Full Name
Cyclin B3provided by FlyBase
Primary source
FLYBASE:FBgn0015625
Locus tag
Dmel_CG5814
See related
AllianceGenome:FB:FBgn0015625
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0118547.414; CG5814; Cyc B3; cycB3; Dmel\CG5814; l(3)L6540
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in mitotic cytokinesis and syncytial blastoderm mitotic cell cycle. Located in nucleus. Is expressed in several structures, including CNS glial cell; antennal anlage; head epidermis primordium; neuroblasts; and ventral nerve cord. Orthologous to human CCNB3 (cyclin B3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CycB3 in Genome Data Viewer
Location:
96B1-96B1; 3-86 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24867934..24870816, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20693656..20696538, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Sting-regulated gene 1 Neighboring gene Elastin-like Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitotic cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitotic cell cycle phase transition IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic cytokinesis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitotic cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in syncytial blastoderm mitotic cell cycle IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
cyclin B3
Names
CG5814-PA
CG5814-PB
CycB3-PA
CycB3-PB
CyclinB3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24867934..24870816 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276005.1NP_001262934.1  cyclin B3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262934.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96718, Q9I7I0, Q9TYG8
    UniProtKB/TrEMBL
    A0A0B4KHT9
    Conserved Domains (2) summary
    pfam00134
    Location:308433
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:435555
    Cyclin_C; Cyclin, C-terminal domain
  2. NM_143046.3NP_651303.2  cyclin B3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651303.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96718, Q9I7I0, Q9TYG8
    UniProtKB/TrEMBL
    A0A0B4KHT9
    Related
    FBpp0084103
    Conserved Domains (2) summary
    pfam00134
    Location:308433
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:435555
    Cyclin_C; Cyclin, C-terminal domain