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CG11069 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42976, updated on 9-Dec-2024

Summary

Official Symbol
CG11069provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039244
Locus tag
Dmel_CG11069
See related
AllianceGenome:FB:FBgn0039244
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
DmCG11069; Dmel\CG11069
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be part of ATP-binding activity cassette (ABC) transporter complex. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; dorsal ectoderm; dorsal epidermis primordium; epithelium; and gut section. Human ortholog(s) of this gene implicated in arteriosclerosis; sitosterolemia 1; and sitosterolemia 2. Orthologous to human ABCG5 (ATP binding cassette subfamily G member 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CG11069 in Genome Data Viewer
Location:
96B4-96B4; 3-86 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24894742..24897613)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20720464..20723335)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44267 Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class S

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG11069-PA
NP_651307.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24894742..24897613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143050.2NP_651307.2  uncharacterized protein Dmel_CG11069 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651307.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MRJ2, Q9VC15
    Related
    FBpp0084089
    Conserved Domains (3) summary
    cd03234
    Location:15233
    ABCG_White; White pigment protein homolog of ABCG transporter subfamily
    COG1131
    Location:31302
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    cl21474
    Location:364515
    ABC2_membrane; ABC-2 type transporter