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Bili Band4.1 inhibitor LRP interactor [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43019, updated on 9-Dec-2024

Summary

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Official Symbol
Biliprovided by FlyBase
Official Full Name
Band4.1 inhibitor LRP interactorprovided by FlyBase
Primary source
FLYBASE:FBgn0039282
Locus tag
Dmel_CG11848
See related
AllianceGenome:FB:FBgn0039282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11848; dBili; Dmel\CG11848
Summary
Involved in negative regulation of canonical Wnt signaling pathway. Colocalizes with plasma membrane. Is expressed in several structures, including anlage in statu nascendi; epithelium; ganglia; head epidermis primordium; and imaginal disc. Orthologous to human FRMD8 (FERM domain containing 8) and FRMD8P1 (FERM domain containing 8 pseudogene 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Bili in Genome Data Viewer
Location:
96C1-96C1; 3-87 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25131306..25136709)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20957028..20962431)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Molybdenum cofactor synthesis 2B Neighboring gene Molybdenum cofactor synthesis 2A Neighboring gene Caliban Neighboring gene long non-coding RNA:CR46098 Neighboring gene distal antenna-related

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6. Kategaya LS, et al. PLoS One, 2009 Jul 2. PMID 19572019, Free PMC Article
  2. Birth of a new gene on the Y chromosome of Drosophila melanogaster. Carvalho AB, et al. Proc Natl Acad Sci U S A, 2015 Oct 6. PMID 26385968, Free PMC Article
  3. Distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila. Emerald BS, et al. Development, 2003 Mar. PMID 12571108
  4. Defining a core set of actin cytoskeletal proteins critical for actin-based motility of Rickettsia. Serio AW, et al. Cell Host Microbe, 2010 May 20. PMID 20478540, Free PMC Article
  5. Drosophila, an emerging model for cardiac disease. Bier E, et al. Gene, 2004 Nov 10. PMID 15527959

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of canonical Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Band4.1 inhibitor LRP interactor
Names
Bili-PB
Bili-PC
Bili-PD
Bili-PE
Bili-PF
Bili-PG
Bili-PH
CG11848-PB
CG11848-PC
CG11848-PD
CG11848-PE
CG11848-PF
CG11848-PG
CG11848-PH
band 4.1 FERM-like

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    25131306..25136709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143085.3 → NP_651342.3  Band4.1 inhibitor LRP interactor, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651342.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  2. NM_001170253.2 → NP_001163724.1  Band4.1 inhibitor LRP interactor, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163724.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  3. NM_001170254.2 → NP_001163725.1  Band4.1 inhibitor LRP interactor, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163725.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  4. NM_001170251.2 → NP_001163722.1  Band4.1 inhibitor LRP interactor, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163722.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  5. NM_001170252.2 → NP_001163723.1  Band4.1 inhibitor LRP interactor, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163723.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  6. NM_001300592.1 → NP_001287521.1  Band4.1 inhibitor LRP interactor, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287521.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain

  7. NM_001170255.1 → NP_001163726.1  Band4.1 inhibitor LRP interactor, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163726.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNK3, Q8SX93, Q9VBX0
    Conserved Domains (2) summary
    smart00295
    Location:432 → 663
    B41; Band 4.1 homologues
    pfam00373
    Location:539 → 663
    FERM_M; FERM central domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VBX0 Q9VBX0

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