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Tnks - tankyrase

Enables NAD+-protein poly-ADP-ribosyltransferase activity. Involved in positive regulation of JNK cascade; positive regulation of canonical Wnt signaling pathway; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in nucleus. Is active in cytosol. Orthologous to human TNKS (tankyrase) and TNKS2 (tankyrase 2). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa