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Nf1 - Neurofibromin 1

Enables GTPase activator activity. Involved in several processes, including Ras protein signal transduction; determination of adult lifespan; and learning or memory. Is expressed in several structures, including adult brain; adult brain cell body rind; adult head; ganglia; and synaptic neuropil domain. Used to study attention deficit hyperactivity disorder; neurofibromatosis; neurofibromatosis 1; and sleep disorder. Human ortholog(s) of this gene implicated in several diseases, including Watson syndrome; autistic disorder; hematologic cancer (multiple); neurofibromatosis 1 (multiple); and peripheral nervous system neoplasm (multiple). Orthologous to human NF1 (neurofibromin 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Nf1

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Species Gene Architecture aa