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Exo84 Exocyst 84 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43163, updated on 9-Dec-2024

Summary

Official Symbol
Exo84provided by FlyBase
Official Full Name
Exocyst 84provided by FlyBase
Primary source
FLYBASE:FBgn0266668
Locus tag
Dmel_CG6095
See related
AllianceGenome:FB:FBgn0266668
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0153538.55; CG6095; DExo84; Dmel\CG6095; exo84; Exo84p; onr
Summary
Involved in several processes, including cytoskeleton-dependent cytokinesis; endocytic recycling; and maintenance of epithelial cell apical/basal polarity. Part of exocyst. Is expressed in adult head. Orthologous to human EXOC8 (exocyst complex component 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Exo84 in Genome Data Viewer
Location:
96F10-96F10; 3-89 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26049731..26052257, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21875453..21877979, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Enhancer of split m7, helix-loop-helix Neighboring gene Enhancer of split m8, helix-loop-helix Neighboring gene groucho Neighboring gene Vacuolar protein sorting 2 Neighboring gene Cytidine/uridine monophosphate kinase 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in Golgi to plasma membrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in actomyosin contractile ring contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endocytic recycling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment or maintenance of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in exocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in maintenance of epithelial cell apical/basal polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiosis I cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiosis II cytokinesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiotic spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neurotransmitter secretion NAS
Non-traceable Author Statement
more info
PubMed 
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synaptic vesicle docking NAS
Non-traceable Author Statement
more info
PubMed 
involved_in synaptic vesicle targeting NAS
Non-traceable Author Statement
more info
PubMed 
involved_in vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of exocyst IDA
Inferred from Direct Assay
more info
PubMed 
part_of exocyst IEA
Inferred from Electronic Annotation
more info
 
part_of exocyst ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of exocyst NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
exocyst 84
Names
CG6095-PA
CG6095-PB
Exo84 ortholog
Exo84-PA
Exo84-PB
onion ring
onion rings

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    26049731..26052257 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143197.2NP_651454.1  exocyst 84, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651454.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H1UUJ5, Q9VBI4
    Related
    FBpp0084350
    Conserved Domains (5) summary
    cd01226
    Location:131241
    PH_RalBD_exo84; Exocyst complex 84-kDa subunit Ral-binding domain/Pleckstrin Homology (PH) domain
    pfam00169
    Location:141233
    PH; PH domain
    pfam05177
    Location:224292
    RCSD; RCSD region
    pfam08700
    Location:489
    Vps51; Vps51/Vps67
    pfam16528
    Location:284484
    Exo84_C; Exocyst component 84 C-terminal
  2. NM_206576.2NP_996299.1  exocyst 84, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996299.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H1UUJ5, Q7KRZ3
    Conserved Domains (5) summary
    cd01226
    Location:132242
    PH_RalBD_exo84; Exocyst complex 84-kDa subunit Ral-binding domain/Pleckstrin Homology (PH) domain
    pfam00169
    Location:142234
    PH; PH domain
    pfam05177
    Location:225293
    RCSD; RCSD region
    pfam08700
    Location:490
    Vps51; Vps51/Vps67
    pfam16528
    Location:285485
    Exo84_C; Exocyst component 84 C-terminal