KLK1 kallikrein 1 [Sus scrofa (pig)] - Gene

Summary

Gene symbol: KLK1
Gene description: kallikrein 1
See related: Ensembl:ENSSSCG00000024668
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Biased expression in kidney (RPKM 173.0) and mixtures (RPKM 31.7) See more
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Genomic context

Location:: chromosome: 6

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	6	NC_010448.4 (55570632..55576398, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	6	NC_010448.3 (51469507..51475249, complement)

Chromosome 6 - NC_010448.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of systemic arterial blood pressure	IEA Inferred from Electronic Annotation more info	PubMed
involved_in zymogen activation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: kallikrein-1

Names: glandular kallikrein; kallikrein 1, renal/pancreas/salivary

NP_001001911.1

EC 3.4.21.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001911.1 → NP_001001911.1 kallikrein-1 precursor

See identical proteins and their annotated locations for NP_001001911.1

Status: PROVISIONAL

Source sequence(s)

AY290706

UniProtKB/TrEMBL

A0A287BI78, A0A4X1VWF6, A0A8D0RE50, Q6H319

Related

ENSSSCP00000055845.1, ENSSSCT00000052328.3

Conserved Domains (2) summary

smart00020
Location:24 → 255

Tryp_SPc; Trypsin-like serine protease

cd00190
Location:25 → 258

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...