nfil3-6 nuclear factor, interleukin 3 regulated, member 6 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nfil3-6provided by ZNC
Official Full Name: nuclear factor, interleukin 3 regulated, member 6provided by ZNC
Primary source: ZFIN:ZDB-GENE-040704-63
See related: Ensembl:ENSDARG00000087188 AllianceGenome:ZFIN:ZDB-GENE-040704-63
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: E4BP4-6; zgc:77060; zgc:103704
Summary: Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within circadian regulation of gene expression and regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in epiphysis; retina; retinal inner nuclear layer; retinal photoreceptor layer; and telencephalon. Orthologous to human NFILZ (NFIL3 like basic leucine zipper). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (14097538..14103553, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (13947694..13953685, complement)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within circadian regulation of gene expression	IDA Inferred from Direct Assay more info	PubMed
involved_in circadian rhythm	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nuclear factor, interleukin 3 regulated, member 6

Names: E4 binding protein 4-6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.