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Tsp97E Tetraspanin 97E [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43241, updated on 4-Jan-2025

Summary

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Official Symbol
Tsp97Eprovided by FlyBase
Official Full Name
Tetraspanin 97Eprovided by FlyBase
Primary source
FLYBASE:FBgn0039465
Locus tag
Dmel_CG6323
See related
AllianceGenome:FB:FBgn0039465
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG6323; Dm.Tsp97E; Dmel\CG6323; Tspan31
Summary
Predicted to be located in membrane. Is expressed in adult head; embryonic brain; larval ventral nerve cord; and organism. Orthologous to human TSPAN13 (tetraspanin 13) and TSPAN31 (tetraspanin 31). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Tsp97E in Genome Data Viewer
Location:
97D11-97D11; 3-92 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (26961064..26964817, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22786786..22790539, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Spag1 axonemal dynein assembly factor Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 97a Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary dynamics of U12-type spliceosomal introns. Lin CF, et al. BMC Evol Biol, 2010 Feb 17. PMID 20163699, Free PMC Article
  2. A Drosophila model of spinal muscular atrophy uncouples snRNP biogenesis functions of survival motor neuron from locomotion and viability defects. Praveen K, et al. Cell Rep, 2012 Jun 28. PMID 22813737, Free PMC Article
  3. An SMN-dependent U12 splicing event essential for motor circuit function. Lotti F, et al. Cell, 2012 Oct 12. PMID 23063131, Free PMC Article
  4. Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Schneider C, et al. Proc Natl Acad Sci U S A, 2004 Jun 29. PMID 15210936, Free PMC Article
  5. Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways. Pessa HK, et al. PLoS One, 2010 Oct 11. PMID 20949011, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
tetraspanin 97E
Names
CG6323-PA
CG6323-PD
CG6323-PE
CG6323-PG
CG6323-PH
Tetraspanin97E
Tsp97E-PA
Tsp97E-PD
Tsp97E-PE
Tsp97E-PG
Tsp97E-PH

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    26961064..26964817 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300621.1 → NP_001287550.1  tetraspanin 97E, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287550.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2J606, Q9VB99
    Conserved Domains (2) summary
    cl02781
    Location:121 → 177
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:7 → 204
    Tetraspannin; Tetraspanin family

  2. NM_170297.3 → NP_733176.2  tetraspanin 97E, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733176.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0Q9, G2J606, Q8IMQ7
    Conserved Domains (2) summary
    cl02781
    Location:121 → 177
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:7 → 210
    Tetraspannin; Tetraspanin family

  3. NM_001276073.1 → NP_001263002.1  tetraspanin 97E, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263002.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2J606, Q9VB99
    Conserved Domains (2) summary
    cl02781
    Location:121 → 177
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:7 → 204
    Tetraspannin; Tetraspanin family

  4. NM_001144643.3 → NP_001138115.2  tetraspanin 97E, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138115.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7Z0Q9, G2J606, Q8IMQ7
    Conserved Domains (2) summary
    cl02781
    Location:121 → 177
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:7 → 210
    Tetraspannin; Tetraspanin family

  5. NM_079800.3 → NP_524524.1  tetraspanin 97E, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524524.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G2J606, Q9VB99
    Related
    FBpp0084454
    Conserved Domains (2) summary
    cl02781
    Location:121 → 177
    tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
    pfam00335
    Location:7 → 204
    Tetraspannin; Tetraspanin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IMQ7 Q8IMQ7
Q9VB99 Q9VB99

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