gb genderblind [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: gbprovided by FlyBase
Official Full Name: genderblindprovided by FlyBase
Primary source: FLYBASE:FBgn0039487
Locus tag: Dmel_CG6070
See related: AllianceGenome:FB:FBgn0039487
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.295; CG6070; Dmel\CG6070; Gb
Summary: Predicted to enable L-amino acid transmembrane transporter activity. Involved in several processes, including chemosensory behavior; glutamate secretion; and male courtship behavior. Located in neuromuscular junction. Is expressed in several structures, including CNS glial cell; adult brain; anterior-posterior subdivision of organism; ganglia; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Orthologous to human SLC7A6 (solute carrier family 7 member 6) and SLC7A7 (solute carrier family 7 member 7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (27108467..27112270, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (22934189..22937992, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

genderblind controls synapse strength and courtship in Drosophila.
Title: A glial amino-acid transporter controls synapse strength and courtship in Drosophila.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables L-amino acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables amino acid transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amino acid transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in amino acid transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in chemosensory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in glutamate secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in male courtship behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phagocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in neuromuscular junction	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain