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Cyp2c68 cytochrome P450, family 2, subfamily c, polypeptide 68 [ Mus musculus (house mouse) ]

Gene ID: 433247, updated on 27-Nov-2024

Summary

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Official Symbol
Cyp2c68provided by MGI
Official Full Name
cytochrome P450, family 2, subfamily c, polypeptide 68provided by MGI
Primary source
MGI:MGI:3612287
See related
Ensembl:ENSMUSG00000074882 AllianceGenome:MGI:3612287
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9030012A22Rik
Summary
Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in liver E18 (RPKM 231.9), liver adult (RPKM 187.3) and 5 other tissues See more
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Genomic context

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See Cyp2c68 in Genome Data Viewer
Location:
19 C3; 19 34.24 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (39677280..39729545, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (39688836..39741101, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 39 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 38 Neighboring gene STARR-seq mESC enhancer starr_46112 Neighboring gene STARR-seq mESC enhancer starr_46113 Neighboring gene STARR-seq mESC enhancer starr_46114 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 67 Neighboring gene STARR-seq mESC enhancer starr_46115 Neighboring gene STARR-seq mESC enhancer starr_46116 Neighboring gene STARR-seq mESC enhancer starr_46117 Neighboring gene STARR-seq mESC enhancer starr_46118 Neighboring gene STARR-seq mESC enhancer starr_46119 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 40 Neighboring gene STARR-seq mESC enhancer starr_46120 Neighboring gene STARR-seq mESC enhancer starr_46121 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 69

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements. Kasai F, et al. Cytogenet Genome Res, 2007. PMID 18160786
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in organic acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in xenobiotic metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytochrome P450, family 2, subfamily c, polypeptide 68
Names
cytochrome P450 2C40 family

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039555.2 → NP_001034644.2  cytochrome P450, family 2, subfamily c, polypeptide 68 precursor

    Status: VALIDATED

    Source sequence(s)
    AI226521, AI256575, AK136413
    Consensus CDS
    CCDS29797.1
    UniProtKB/TrEMBL
    K7N6C2, Q8VCP4
    Related
    ENSMUSP00000097071.4, ENSMUST00000099472.4
    Conserved Domains (1) summary
    pfam00067
    Location:30 → 487
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    39677280..39729545 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527177.2 → XP_006527240.1  cytochrome P450, family 2, subfamily c, polypeptide 68 isoform X1

    UniProtKB/TrEMBL
    Q8VCP4
    Conserved Domains (1) summary
    pfam00067
    Location:1 → 433
    p450; Cytochrome P450
Nucleotide Protein Strain
Heading Accession and Version

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