U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG12259 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43347, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG12259provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039557
Locus tag
Dmel_CG12259
See related
AllianceGenome:FB:FBgn0039557
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12259
Summary
Predicted to enable RNA binding activity. Predicted to be involved in chromatin organization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in organism. Human ortholog(s) of this gene implicated in Armfield syndrome. Orthologous to human FAM50A (family with sequence similarity 50 member A) and FAM50B (family with sequence similarity 50 member B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG12259 in Genome Data Viewer
Location:
98B6-98B6; 3-94 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27919844..27921089, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (23745566..23746811, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene milkah Neighboring gene uncharacterized protein Neighboring gene mitochondrial ribosomal protein S22 Neighboring gene Buddy of Hmr 1 Neighboring gene BCAS2 Neighboring gene ncRNA Neighboring gene Ribosomal protein L4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Regulatory network in heat stress response in parasitoid wasp focusing on Xap5 heat stress regulator. Xiong S, et al. iScience, 2024 Jan 19. PMID 38205256, Free PMC Article
  2. Whole transcriptome screening for novel genes involved in meiosis and fertility in Drosophila melanogaster. Sun S, et al. Sci Rep, 2024 Feb 13. PMID 38351116, Free PMC Article
  3. Border cell polarity and collective migration require the spliceosome component Cactin. Miao G, et al. J Cell Biol, 2022 Jul 4. PMID 35612426, Free PMC Article
  4. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
  5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in chromatin organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG12259-PA

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    27919844..27921089 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143338.3 → NP_651595.1  uncharacterized protein Dmel_CG12259 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651595.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VAY7
    Related
    FBpp0084639
    Conserved Domains (1) summary
    pfam04921
    Location:110 → 351
    XAP5; XAP5, circadian clock regulator
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VAY7.1 Q9VAY7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous