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snu snustorr [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43391, updated on 9-Dec-2024

Summary

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Official Symbol
snuprovided by FlyBase
Official Full Name
snustorrprovided by FlyBase
Primary source
FLYBASE:FBgn0039594
Locus tag
Dmel_CG9990
See related
AllianceGenome:FB:FBgn0039594
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG9990; DmCG9990; Dmel\CG9990; Snu
Summary
Predicted to enable ABC-type transporter activity; ATP binding activity; and ATP hydrolysis activity. Involved in cuticle development. Located in apical plasma membrane and cytoplasmic vesicle. Is expressed in several structures, including adult head; embryonic anal pad; embryonic head epidermis; epithelium; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See snu in Genome Data Viewer
Location:
98E1-98E2; 3-97 cM
Exon count:
13
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28675041..28695939)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24500763..24521661)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Stress induced DNase Neighboring gene huntingtin Neighboring gene Allatostatin A receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dysfunction of Oskyddad causes Harlequin-type ichthyosis-like defects in Drosophila melanogaster. Wang Y, et al. PLoS Genet, 2020 Jan. PMID 31929524, Free PMC Article
  2. Characterization of axonal transport defects in Drosophila Huntingtin mutants. Weiss KR, et al. J Neurogenet, 2016 Sep-Dec. PMID 27309588, Free PMC Article
  3. The ABC transporter Snu and the extracellular protein Snsl cooperate in the formation of the lipid-based inward and outward barrier in the skin of Drosophila. Zuber R, et al. Eur J Cell Biol, 2018 Mar. PMID 29306642
  4. Characterization of the Drosophila ortholog of the human Usher Syndrome type 1G protein sans. Demontis F, et al. PLoS One, 2009. PMID 19270738, Free PMC Article
  5. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Zhang S, et al. Dis Model Mech, 2009 May-Jun. PMID 19380309, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cuticle development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
snustorr
Names
CG9990-PA
CG9990-PB
CG9990-PD
CG9990-PE
CG9990-PF
CG9990-PG
snu-PA
snu-PB
snu-PD
snu-PE
snu-PF
snu-PG

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    28675041..28695939
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143371.2 → NP_651628.1  snustorr, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651628.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VAU1
    Related
    FBpp0084677
    Conserved Domains (5) summary
    cd03230
    Location:74 → 286
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:73 → 290
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    cl19580
    Location:427 → 474
    pip_yhgE_Nterm; YhgE/Pip N-terminal domain
    pfam01061
    Location:601 → 769
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:429 → 801
    ABC2_membrane_3; ABC-2 family transporter protein

  2. NM_170376.1 → NP_733255.1  snustorr, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733255.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMM1
    Related
    FBpp0084678, FBtr0085309
    Conserved Domains (5) summary
    cd03230
    Location:43 → 255
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:42 → 259
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    cl19580
    Location:396 → 443
    pip_yhgE_Nterm; YhgE/Pip N-terminal domain
    pfam01061
    Location:570 → 738
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:398 → 770
    ABC2_membrane_3; ABC-2 family transporter protein

  3. NM_001202376.1 → NP_001189305.1  snustorr, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189305.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JD13
    Conserved Domains (4) summary
    cd03230
    Location:43 → 255
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:42 → 259
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    pfam01061
    Location:556 → 724
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:386 → 756
    ABC2_membrane_3; ABC-2 family transporter protein

  4. NM_001276111.1 → NP_001263040.1  snustorr, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263040.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KHS4
    Conserved Domains (4) summary
    cd03230
    Location:32 → 244
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:31 → 248
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    pfam01061
    Location:557 → 725
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:387 → 757
    ABC2_membrane_3; ABC-2 family transporter protein

  5. NM_001260422.1 → NP_001247351.1  snustorr, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247351.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B9EQW2
    Conserved Domains (4) summary
    cd03230
    Location:43 → 255
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:42 → 259
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    pfam01061
    Location:568 → 736
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:398 → 768
    ABC2_membrane_3; ABC-2 family transporter protein

  6. NM_001260421.1 → NP_001247350.1  snustorr, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247350.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4K7B3
    Conserved Domains (5) summary
    cd03230
    Location:32 → 244
    ABC_DR_subfamily_A; ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A
    COG1136
    Location:31 → 248
    LolD; ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]
    cl19580
    Location:385 → 432
    pip_yhgE_Nterm; YhgE/Pip N-terminal domain
    pfam01061
    Location:559 → 727
    ABC2_membrane; ABC-2 type transporter
    pfam12698
    Location:387 → 759
    ABC2_membrane_3; ABC-2 family transporter protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4JD13 A0A0B4JD13
A0A0B4K7B3 A0A0B4K7B3
A0A0B4KHS4 A0A0B4KHS4
B9EQW2 B9EQW2
Q86LC8 Q86LC8
Q8IMM1 Q8IMM1
Q9VAU1 Q9VAU1

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