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htt - huntingtin

Involved in several processes, including establishment of mitotic spindle orientation; heterochromatin boundary formation; and synaptic vesicle transport. Located in cytoplasm. Is expressed in imaginal disc; larval central nervous system; and organism. Used to study Huntington's disease and neurodegenerative disease. Human ortholog(s) of this gene implicated in Huntington's disease and Parkinson's disease. Orthologous to human HTT (huntingtin). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa