WASp - WASp
Predicted to enable small GTPase binding activity. Involved in several processes, including axon development; cytoskeleton organization; and epithelial cell differentiation. Located in several cellular components, including microvillus; neuromuscular junction; and rhabdomere. Part of protein-containing complex. Is expressed in several structures, including adult head; embryonic salivary gland duct; embryonic ventral epidermis; embryonic/larval neuromuscular junction; and epithelium. Human ortholog(s) of this gene implicated in Wiskott-Aldrich syndrome; X-linked severe congenital neutropenia; and thrombocytopenia. Orthologous to several human genes including WAS (WASP actin nucleation promoting factor). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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