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Ccnb1-ps cyclin B1, pseudogene [ Mus musculus (house mouse) ]

Gene ID: 434175, updated on 2-Nov-2024

Summary

Official Symbol
Ccnb1-psprovided by MGI
Official Full Name
cyclin B1, pseudogeneprovided by MGI
Primary source
MGI:MGI:3648694
See related
Ensembl:ENSMUSG00000048574 AllianceGenome:MGI:3648694
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5593; EG434175
Summary
Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Predicted to be involved in several processes, including mitotic metaphase chromosome alignment; positive regulation of mitochondrial ATP synthesis coupled electron transport; and regulation of cell cycle process. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleus. Predicted to be part of cyclin B1-CDK1 complex and outer kinetochore. Predicted to colocalize with mitochondrial matrix. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Ccnb1-ps in Genome Data Viewer
Location:
7 B3; 7 28.25 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (41755193..41756726, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (42105769..42107302, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor 59 Neighboring gene high-mobility group high mobility group box 1, pseudogene 7 Neighboring gene F-box protein 34 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18736 Neighboring gene vomeronasal 2, receptor 60 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene vomeronasal 2, receptor 61

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity ISO
Inferred from Sequence Orthology
more info
 
enables patched binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin-like protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
part_of cyclin B1-CDK1 complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of outer kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
G2/mitotic-specific cyclin-B1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    41755193..41756726 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153675.1XP_036009568.1  G2/mitotic-specific cyclin-B1-like

    UniProtKB/TrEMBL
    Q3TFV6, Q3UWL3
    Related
    ENSMUST00000155338.2
    Conserved Domains (2) summary
    cd20565
    Location:164292
    CYCLIN_CCNB1_rpt1; first cyclin box found in G2/mitotic-specific cyclin-B1 (CCNB1)
    cl40454
    Location:297417
    CYCLIN_SF; Cyclin box fold superfamily