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Zfp560 zinc finger protein 560 [ Mus musculus (house mouse) ]

Gene ID: 434377, updated on 27-Nov-2024

Summary

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Official Symbol
Zfp560provided by MGI
Official Full Name
zinc finger protein 560provided by MGI
Primary source
MGI:MGI:1915280
See related
Ensembl:ENSMUSG00000045519 AllianceGenome:MGI:1915280
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf560; 2310030G09Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF560 (zinc finger protein 560). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E18 (RPKM 3.2), CNS E14 (RPKM 2.9) and 24 other tissues See more
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Genomic context

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See Zfp560 in Genome Data Viewer
Location:
9 A3; 9 7.52 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20256432..20296479, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (20345136..20385182, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily E member 177 Neighboring gene STARR-seq mESC enhancer starr_23456 Neighboring gene olfactory receptor family 7 subfamily E member 178 Neighboring gene STARR-positive B cell enhancer ABC_E9752 Neighboring gene zinc finger protein 26 Neighboring gene STARR-positive B cell enhancer ABC_E9753 Neighboring gene zinc finger protein 426 Neighboring gene predicted gene, 23316

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 778

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004190.4 → NP_001004190.2  zinc finger protein 778

    See identical proteins and their annotated locations for NP_001004190.2

    Status: VALIDATED

    Source sequence(s)
    AC166098
    Consensus CDS
    CCDS22877.1
    UniProtKB/TrEMBL
    Q3URI6
    Related
    ENSMUSP00000065620.8, ENSMUST00000068079.14
    Conserved Domains (6) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:276 → 689
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:617 → 637
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:279 → 301
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:41 → 80
    KRAB; KRAB box
    pfam13465
    Location:293 → 318
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    20256432..20296479 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244440.2 → XP_030100300.1  zinc finger protein 778 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:70 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:411 → 431
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_030244441.2 → XP_030100301.1  zinc finger protein 778 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:70 → 483
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:411 → 431
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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