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Drice - Death related ICE-like caspase

Enables BIR domain binding activity; cysteine-type endopeptidase activity involved in execution phase of apoptosis; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of signal transduction; neuron remodeling; and nurse cell apoptotic process. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including central brain primordium; cystic bulge; embryonic/larval midgut; embryonic/larval midgut primordium; and ganglia. Human ortholog(s) of this gene implicated in breast cancer; gastrointestinal system cancer (multiple); lung non-small cell carcinoma; and neurodegenerative disease (multiple). Orthologous to human CASP3 (caspase 3) and CASP7 (caspase 7). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to Drice

NCBI Orthologs

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Species Gene Architecture aa