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Rsod Related to Sod [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43586, updated on 9-Dec-2024

Summary

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Official Symbol
Rsodprovided by FlyBase
Official Full Name
Related to Sodprovided by FlyBase
Primary source
FLYBASE:FBgn0051028
Locus tag
Dmel_CG31028
See related
AllianceGenome:FB:FBgn0051028
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2176; CG31028; Dmel\CG31028; SOD
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in superoxide metabolic process. Is expressed in several structures, including dorsal epidermis primordium; embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Rsod in Genome Data Viewer
Location:
99E1-99E1; 3-100 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30166631..30171207, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (25992353..25996929, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene VhaAC45-related protein Neighboring gene Myosin light chain 2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Superoxide dismutase evolution and life span regulation. Landis GN, et al. Mech Ageing Dev, 2005 Mar. PMID 15664623
  2. Distribution and diversity of ROS-generating enzymes across the animal kingdom, with a focus on sponges (Porifera). Hewitt OH, et al. BMC Biol, 2022 Sep 30. PMID 36175868, Free PMC Article
  3. Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila. Ambrus AM, et al. Genetics, 2009 Sep. PMID 19546319, Free PMC Article
  4. Icaritin greatly attenuates β-amyloid-induced toxicity in vivo. Li L, et al. CNS Neurosci Ther, 2024 Apr. PMID 37990437, Free PMC Article
  5. Gene expression profiling of Drosophila tracheal fusion cells. Chandran RR, et al. Gene Expr Patterns, 2014 Jul. PMID 24928808

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables superoxide dismutase activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_733352.3
  • related to Sod

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    30166631..30171207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170473.3 → NP_733352.3  uncharacterized protein Dmel_CG31028 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733352.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    I0C0N1, Q9VA99
    Conserved Domains (2) summary
    pfam00080
    Location:696 → 825
    Sod_Cu; Copper/zinc superoxide dismutase (SODC)
    cl00891
    Location:518 → 676
    Cu-Zn_Superoxide_Dismutase; Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VA99 Q9VA99

Gene LinkOut

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