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CG15539 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43627, updated on 9-Dec-2024

Summary

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Official Symbol
CG15539provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039782
Locus tag
Dmel_CG15539
See related
AllianceGenome:FB:FBgn0039782
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15539-NE4; Dmel\CG15539
Summary
Predicted to enable procollagen-proline 4-dioxygenase activity. Predicted to be active in endoplasmic reticulum. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG15539 in Genome Data Viewer
Location:
99F6-99F6; 3-100 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30505987..30507977)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26331709..26333699)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene prolyl-4-hydroxylase-alpha SG1 Neighboring gene mir-4908 stem loop Neighboring gene uncharacterized protein Neighboring gene prolyl-4-hydroxylase-alpha NE2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Prolyl 4-hydroxylase alpha-related proteins in Drosophila melanogaster: tissue-specific embryonic expression of the 99F8-9 cluster. Abrams EW, et al. Mech Dev, 2002 Mar. PMID 11850189
  2. Fork head and Sage maintain a uniform and patent salivary gland lumen through regulation of two downstream target genes, PH4alphaSG1 and PH4alphaSG2. Abrams EW, et al. Development, 2006 Sep. PMID 16914497
  3. Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. Chung WJ, et al. Genome Res, 2011 Feb. PMID 21177960, Free PMC Article
  4. Research gaps and new insights in the evolution of Drosophila seminal fluid proteins. Hurtado J, et al. Insect Mol Biol, 2022 Apr. PMID 34747062
  5. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables procollagen-proline 4-dioxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables procollagen-proline 4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15539-PA
CG15539-PB
CG15539-PC
NP_001036776.1
NP_001287615.1
NP_651804.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    30505987..30507977
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143547.3 → NP_651804.2  uncharacterized protein Dmel_CG15539, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651804.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V443, Q9VA62
    Conserved Domains (2) summary
    smart00702
    Location:206 → 371
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:1 → 33
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. NM_001043311.2 → NP_001036776.1  uncharacterized protein Dmel_CG15539, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036776.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHY7
    Conserved Domains (2) summary
    smart00702
    Location:329 → 494
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:33 → 156
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. NM_001300686.1 → NP_001287615.1  uncharacterized protein Dmel_CG15539, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287615.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LHW6
    Conserved Domains (2) summary
    smart00702
    Location:328 → 493
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:33 → 156
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LHW6 A0A0B4LHW6
Q0KHY7 Q0KHY7
Q4V443 Q4V443

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