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CG15543 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43647, updated on 4-Jan-2025

Summary

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Official Symbol
CG15543provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039799
Locus tag
Dmel_CG15543
See related
AllianceGenome:FB:FBgn0039799
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15543
Summary
Predicted to enable adenylate kinase activity. Predicted to be active in cytoplasm. Is expressed in adult head and spermatozoon. Orthologous to human AK8 (adenylate kinase 8). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG15543 in Genome Data Viewer
Location:
100A3-100A3; 3-101 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30742880..30744474)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26568602..26570196)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4H2 Neighboring gene uncharacterized protein Neighboring gene Niemann-Pick type C-2g Neighboring gene Niemann-Pick type C-2h

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift. Cingolani P, et al. Front Genet, 2012. PMID 22435069, Free PMC Article
  2. Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Ringrose L, et al. Dev Cell, 2003 Nov. PMID 14602076
  3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
  5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables adenylate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables adenylate kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15543-PA
CG15543-PB
NP_001287617.1
NP_651822.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    30742880..30744474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300688.1 → NP_001287617.1  uncharacterized protein Dmel_CG15543, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287617.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K046, Q9VA43
    Conserved Domains (1) summary
    cl17190
    Location:89 → 213
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. NM_143565.3 → NP_651822.1  uncharacterized protein Dmel_CG15543, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651822.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K046, Q9VA43
    Related
    FBpp0085062
    Conserved Domains (1) summary
    cl17190
    Location:89 → 213
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K046 Q7K046
Q9VA43 Q9VA43

Gene LinkOut

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