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Ktch Ketchup [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43681, updated on 4-Jan-2025

Summary

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Official Symbol
Ktchprovided by FlyBase
Official Full Name
Ketchupprovided by FlyBase
Primary source
FLYBASE:FBgn0039821
Locus tag
Dmel_CG15556
See related
AllianceGenome:FB:FBgn0039821
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0170980.178; anon-WO0170980.179; AT07595p; CG15556; Dmel\CG15556
Summary
Predicted to enable G protein-coupled receptor activity and mechanoreceptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Is active in plasma membrane. Is expressed in adult head. Orthologous to human ADGRG7 (adhesion G protein-coupled receptor G7). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Ktch in Genome Data Viewer
Location:
100B3-100B3; 3-102 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (31127965..31130666, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26953687..26956388, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Proteasome alpha3 subunit, Testis-specific Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46207 Neighboring gene long non-coding RNA:CR43458

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Parallel Genomic Engineering of Two Drosophila Genes Using Orthogonal attB/attP Sites. Blanco-Redondo B, et al. G3 (Bethesda), 2018 Aug 30. PMID 30065043, Free PMC Article
  2. The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila. Vieira Contreras F, et al. Cell Rep, 2024 Jan 23. PMID 38180839
  3. Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. Scholz N, et al. Nature, 2023 Mar. PMID 36890234
  4. Comparative genomic analysis and evolution of family-B G protein-coupled receptors from six model insect species. Li C, et al. Gene, 2013 Apr 25. PMID 23428791
  5. Family-B G-protein-coupled receptors. Harmar AJ. Genome Biol, 2001. PMID 11790261, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mechanoreceptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transmembrane signaling receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
ketchup
Names
CG15556-PA
CG15556-PB
CG15556-PC
Ktch-PA
Ktch-PB
Ktch-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    31127965..31130666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143588.2 → NP_651845.2  ketchup, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651845.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T4B2, Q9VA10
    Related
    FBpp0085099, FBtr0085737
    Conserved Domains (1) summary
    cl21561
    Location:481 → 703
    7tm_4; Olfactory receptor

  2. NM_001260450.1 → NP_001247379.1  ketchup, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247379.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T4B2, Q9VA10
    Conserved Domains (1) summary
    cl21561
    Location:481 → 703
    7tm_4; Olfactory receptor

  3. NM_001260451.1 → NP_001247380.1  ketchup, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247380.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T4B2, Q9VA10
    Conserved Domains (1) summary
    cl21561
    Location:481 → 703
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T4B2 Q8T4B2
Q9VA10 Q9VA10

Gene LinkOut

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