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tyw3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

Gene ID: 436884, updated on 4-Jan-2025

Summary

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Official Symbol
tyw3provided by ZNC
Official Full Name
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)provided by ZNC
Primary source
ZFIN:ZDB-GENE-040718-355
See related
Ensembl:ENSDARG00000038222 AllianceGenome:ZFIN:ZDB-GENE-040718-355
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:92277
Summary
Predicted to enable tRNA methyltransferase activity. Predicted to be involved in tRNA methylation and wybutosine biosynthetic process. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be active in cytoplasm. Orthologous to human TYW3 (tRNA-yW synthesizing protein 3 homolog). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See tyw3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (11119365..11126221)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (11335788..11342622)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 151 member A Neighboring gene leucine rich repeat containing 53 Neighboring gene crystallin, zeta (quinone reductase) Neighboring gene solute carrier family 44 member 5a Neighboring gene LIM homeobox 8a Neighboring gene uncharacterized LOC108179505

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in wybutosine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
tRNA wybutosine-synthesizing protein 3 homolog
Names
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
tRNA-yW-synthesizing protein 3
NP_001002611.1
XP_005171216.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002611.1 → NP_001002611.1  tRNA wybutosine-synthesizing protein 3 homolog

    See identical proteins and their annotated locations for NP_001002611.1

    Status: PROVISIONAL

    Source sequence(s)
    BC075981
    UniProtKB/Swiss-Prot
    A5PN41, Q6DHJ1
    Related
    ENSDARP00000055736.4, ENSDART00000055737.5
    Conserved Domains (1) summary
    pfam02676
    Location:9 → 193
    TYW3; Methyltransferase TYW3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    11119365..11126221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005171159.5 → XP_005171216.1  tRNA wybutosine-synthesizing protein 3 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8M2BIJ6
    Conserved Domains (1) summary
    pfam02676
    Location:9 → 198
    TYW3; Methyltransferase TYW3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6DHJ1.1 GenPept UniProtKB/Swiss-Prot:Q6DHJ1

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